Scientists
rRNA & ribosomes
Regulation and Regulatory Systems
Mutations
Regulation and Regulatory Systems
100

The scientist(s) that discovered transformation in bacteria

What is Frederick Griffith

100

The role of 16S rRNA (ribosomal binding site)

What is it binds to Shine-Dalgarno site on mRNA for protein synthesis initiation & binds protein needed 

BONUS = serves as a molecular clock for bacterial species when determine evolutionary distance among species

100

The description of Negative control Inducible Genes

What is the repressor is bound to the promoter region but once a inducer is present, the repressor is no longer bound & transcription can occur  

100

The type of mutation where there is a change in the nuceoside sequence of codon but not the encoded amino acid

What is Silent Mutation

100

The definition of Attenuation

What is termination of transcription within the leader region (leader peptide)

BONUS: this was first demonstrated with trp operon

200

The scientist(s) that showed that the transforming substance is DNA

What is Oswald Avery and his colleagues

200

The role of 23S rRNA

What is it catalyzes peptide bond formation

200

The description of Positive Control Inducible Genes

What is the activator protein is not bound to the activator binding site but once a inducer is present the activator protein can bind & transcription can occur

200

The type of mutation where a single base substation occurs that changes codon for one amino acid into a codon for another amino acid

What is Missense mutation

200

The type of regulatory system used with the Trp Operon

What is Negative Control of Repressible Genes

300

The scientist(s) that discovered the complementary bases and antiparallel nature of DNA

What is James Watson, Francis Crick & Maurice Wilkins

300

The placement of the 16S rRNA and 23S rRNA on the ribosome

What is the 16S is a part of 30S subunit and 23S is a part of 50S subunit.

300

The description of Negative Control Repressible Genes

what is the repressor is not bound to the promoter region but once a corepressor is introduced the repressor can bind & transcription is stoped

300

The areas where Insertions and Deletions are most likely to occur

What is usually occurring in areas of repeated sequences where strand can become displaced

300

The function of restriction endonuclease

What is an enzyme that destroys viral DNA & in archaea and bacteria targeted through genetic engineering and are analogous to Innate Immune System

400

The scientist(s) that used X-ray crystallography to determine that DNA is a double helix

What is Rosalind Franklin

400

The two functional domains of the ribosome

What is translation domain which is on both subunits and exit domain

400

The description of Positive Control Repressible Genes

What is the activator protein is bound to the activator binding site but once a inhibitor is introduced, the activator protein is no longer bound & transcription is stoped

400

The type of mutation where a sense codon is converted to a nonsense codon

What is Nonsense Mutation

400

The description of Riboswitches

What is function in transcriptional termination in Gram Positive Bacteria & regulate translation of mRNA in Gram Negative bacteria

500

The scientist(s) that discovered Operons

What is Jacques Monod and Francois Jacob

500

The description of the peptidyl site

What is the donor site where it binds initator tRNA or tRNA attached to growing polypeptide  (peptidyl-tRNA)

500

The type of regulatory system used with the Lac Operon

What is Negative Control of Inducible Genes

500

The function of the trp operon

What is it ONLY function in the absence of tryptophan and consists of 5 structural genes which code for enzymes needed to synthesize tryptophan