Welcome to Micro, Enjoy your stay.
(Unit 1)
You're a Eukaryote
(Unit 2)
We Go Together Like Adenine and Thymine
(Unit 3)
Now that we've turned you into a germaphobe, let us introduce you to the Immune System
Stuff You Don't Want To Catch (clinical applications)
100

Give examples as to why microbes are beneficial to humans/the world. 

They:
- are used in producing foods such as cheese and bread
- they are used in industries such as mining and biotechnology.
- they train the immune system and form mutualistic relationships with humans and other animals
- Many more

100

What are the four major macromolecules found in ALL cells?

Lipids, Carbohydrates, Proteins and Nucleic Acids

100

This kind of bond forms the backbone of both DNA and RNA

What are phosphodiester bonds?

100

These are the 5 cardinal signs of inflammation

What are:
- Rubor/erythema/redness
- Calor/heat
- Pain
- Swelling (tumor)
- Altered function

100

This bacterial pathogen affects the nervous system, leading to headache, arching of back and muscle stiffness. 

What is Clostridium tetani?

200

What is a pathogen?

Any infectious agent of disease.

200

How many ATPs are made as a result of oxidative level phosphorylation?

36-38 ATPs

200

These contain genetic information that isn't necessary for life, but may contain beneficial information, like drug resistance.

What are plasmids?

200

While typing your patient for a blood transfusion, you determine that their RBCs have no antigens on their surface, and their serum contains Anti-A and Anti-B antibodies. You also note a lack of Anti-Rh antibodies in their serum. What is your patient's blood type? 

O+

DAILY DOUBLE: What blood types can safely donate to your patient?

200

This bacterium is responsible for the raging sore throats I used to get in grade school. It can also cause impetigo, toxic shock syndrome, scarlet fever and necrotizing fasciitis. 

What is Streptococcus pyogenes?

300

What might happen to a cell lacking a wall if it is placed into a hypertonic solution?

Water will exit the cell, which could cause cell death via crenation.

DAILY DOUBLEEEEE: What if a cell does have a wall, and it is placed in a hypotonic solution?

300

While out studying snow samples from Antarctica, you discover a new bacterium! I hope you name it after your beloved SI Leader! What term would you use to describe its cardinal temperature?

Psychrophile!


DAILY DOUBLEEEE: Upon further research, you realize that this new microbe isn't a bacterium at all! It's actually an archaea! Why might this be the case?

300

If B. cereus has 18% Adenine in its DNA, what percent is composed of uracil?

There is no uracil in DNA ;)

DAILY DOUBLE: Now that I've tried to trick you, let's determine what percentage of B. Cereus is Guanine, Cytosine and Thymine! 

300

Opsonization (c3b), Inflammation (c3a & c5a) and Lysis via membrane attack complex (c5-c9) are the end result of this.

What is complement activation?
(make sure you know what activates it too!)

300

This bacteria can cross the placenta and causes numerous birth defects, including saber shins and saddle nose.

What is Treponema pallidum?

400

You have determined that your patient is in the prodromal phase of infectious disease. How might your patient be feeling?

Your patient will have vague, generalized symptoms. They may feel tired, fatigued. 

400

This is an reproduction method found in some protozoans. It involves multiple mitoses without cytokinesis.

What is schizogony?

400

This states that the flow of genetic information goes from DNA -> RNA -> Protein. 

What is the Central Dogma Theory?

400

Addison’s disease, Celiac, Psoriasis, lupus, rheumatoid arthritis and type I diabetes are examples of these:

Autoimmune disorders

400

Signs and symptoms of this pathogen include fever, swollen lymph nodes and extreme lethargy. It has a biological vector: the tsetse fly.

What is Trypanosoma brucei

500

Pathogen A has an LD 50 of 100, whereas Pathogen B has a LD 50 of 1000. Which one of these pathogens is the least virulent?

Pathogen B. Why?

500

Compare and contrast cysts and endospores

Endospores: A dormant state seen in some G+ bacterial species in response to suboptimal conditions. They are hardier than cysts.

Cysts: Formed by some protozoans. They are also dormant, but not as hardy as endospores.

DAILY DOUBLE: What about conidiospores? 

500

This component of an amino acid is what differentiates it from other amino acids

What are R groups?

500

Provide 3 ways in which antibodies inactivate/neutralize their targets

Neutralization
Opsonization
Oxidation
Complement Activation
Agglutination
ADCC

500

If you were bitten by a female anopheles mosquito, you might become infected with this eukaryotic microbe.

What is Plasmodium