Show:
Viruses
1st & 2nd line defenses
Adaptive Immunity
Famous people
Genetic Change
100
viral structure made of nucleic acid and protein
What is nucleocapsid
100
These enzymes or proteins are part of the first line of defense and found in mucous secretions, tears, or saliva--name one.
What are lysozyme, defensins, lactoferrin, peroxidase.
100
This cell is involved in both the innate and adaptive immune response.
What is a macrophage?
100
He developed the fist successful vaccines for smallpox
Who is Jenner
100
Recombination that involves recA and and a long stretch of similar sequence
What is homologous recombination
200
the first viral disease determined to be transmitted by an insect vector
What is yellow fever
200
These phagocytic cells are involved in the inflammatory response and make up the majority of pus.
What are neutrophils?
200
This role of antibodies marks an antigen for phagocytosis.
What is opsonization?
200
He crystallized TMV
Who is Wendell Stanley?
200
This type of plasmid gives bacteria the ability to cause more disease
What is a virulence plasmid?
300
This plus sense RNa virus makes a polyprotein as part of its replication strategy.
What is poliovirus?
300
This membrane compartment in a macrophage encases the foreign invader and fuses with a lysosome
That is a phagosome?
300
Macrophages use this protein apparatus to display antigens to T cells.
What is MHC-I?
300
He discovered how B cell gene segments are spliced to created different antibody genes.
Who is Susumi Tonegawa?
300
This form of mating results from an integration and faulty excision of the F plasmid, resulting in only a few genes being transferred
What is F' x F minus mating?
400
This virus must being in an RNA-dependent RNA polymerase to replicate?
What is influenza (or rabies or rotavirus)?
400
These cells in the innate immune system target viral infected cells or cancer cells and use perforin to inject signals to "commit suicide."
What are natural killer cells?
400
The activation and multiplication of only the "correct" type of B cell or T cell upon antigen encounter.
What is clonal selection?
400
He discovered phagocytosis
Who is Metchnikoff?
400
The two types of genes carried by a replicative transposon allowing it to "jump"
What are transposase and resolves?
500
This virus must repair and complete its genome after entering the cell it infects, and uses RNA to replicate its genome during infection.
What is hepatitis B virus? (100 pt Bonus: what unique strategy does it use to evade our immune system?)
500
These chemical signals produced by macrophages result in a raising of the core temperature by the hypothalamus.
What are endogenous pyrogens?
500
These two ties of antibodies can activate complement
What are IgG and IgM?
500
He led the team to show that mosquitos transmit yellow fever.
Who is Walter Reed?
500
Term for the ability of a bacterium to produce a toxin encoded by a prophage
What is lysogenic conversion? (100 pt bonus for a specific example).