Cell energy basics
What is Mitochondrial Disease?
Symptoms
Diagnosis and testing
Real life Mito stories
100

What organelle is known as the “powerhouse of the cell”?

What is the mitochondria?

100

Mitochondrial disease is mainly caused by problems with what inside cells?

What is energy production?

100

What is the most common symptom related to energy problems?

What is tiredness?

100

There is currently no cure, but doctors try to do this to symptoms.

What is manage / slow them?

100

Some babies with mitochondrial disease seem healthy at birth but later become very tired and stop eating.

What is early symptom development?

200

What molecule is the main energy currency cells use?

What is ATP?

200

Are mitochondrial diseases usually genetic or caused by injury?

What is genetic?

200

Name one muscle symptom of mitochondrial disease.

What is muscle weakness or muscle pain?

200

Some patients take these to help cell function.

What are vitamins / supplements?

200

Some children with mitochondrial disease need this machine to help them breathe.

What is a ventilator / breathing machine?

300

What process inside mitochondria makes most ATP for cells?

What is the electron transport chain

300

Can mitochondrial disease affect one organ or multiple organs?

What is multiple organs?

300

Name one sense that can be affected.

What is vision or hearing?
300

Doctors often start testing using this body fluid.

What is blood?

300

Some kids with mitochondrial disease experience these sudden brain events caused by low energy.

What are seizures or stroke-like episodes?

400

Why are brain and muscle cells often affected first in mitochondrial disease?

What is they need a lot of energy?

400

True or False: mitochondrial disease can appear at any age.

what is TRUE?

400

Name one neurological symptom.

What is seizures, migraines, or developmental delay?

400

This scan can show problems in the brain structure.

What is an MRI?

400

Families of kids with mitochondrial disease may spend weeks at a time in this place for treatment.

What is the hospital?

500

What happens to cells if mitochondria can’t make enough ATP?

What is cells and organs can’t function properly or may be damaged?

500

Some mitochondrial DNA is inherited only from which parent?

Mother

500

Why do symptoms vary a lot between people?

What is different cells have different amounts of healthy mitochondria?

500

Doctors may test hearing and this other sense affected by mitochondrial disease.

What is vision?

500

Why can mitochondrial disease affect many organs at once?

Because mitochondria provide energy for almost all cells in the body.