what
when
where
why
how
100

what are the roles of cell division?

reproduction, growth and development, tissue repair and renewal

100

in meiosis, when do sister chromatids become genetically distinct?

prophase I

100

where are the chromosomes in metaphase?

chromosomes are lined up along the midline of the cell (metaphase plate)

100

why is DNA coiled and condensed into chromosomes during the mitotic phase?

coiling protects DNA from damage and breakage 
100

how do single-celled eukaryotic organisms produce genetically identical copies of themselves?

mitosis

200

what form does DNA exist in when the cell is NOT dividing?

chromatin

200

when is DNA duplicated?

S phase

200

where do microtubules attach to chromatids?

kinetochores

200

why aren't daughter cells the same size as mother cells?

cytokinesis is the division of cytoplasm and results in daughter cells roughly half the size of the mother cell

200

how do organelles (e.g., mitochondria) replicate?

binary fission
300

what is separated in meiosis I?

homologous chromosomes
300

when does a tumor become malignant?

cancer cells lose attachment to surrounding cells and travel to other tissues through the blood or lymphatic vessels

300

where are sister chromatids connected to each other?

centromere

300

why are cell cycle checkpoints important?

to make sure the cell only divides when it is supposed to

300
how is the cell cycle regulated?

cell cycle checkpoints 

G1 = size

G2 = DNA damage or replication errors

M = chromosome alignment on the spindle

400

what is synapsis?

the pairing of homologous chromosomes (tetrad = four sister chromatids)

400

when do chromosomes decondense?

telophase

400

where does crossing over happen?

chiasma

400

why is meiosis important?

meiosis contributes to genetic variation in populations through crossing over, independent assortment of chromosomes, and random fertilization
400

how are mitosis and meiosis involved in sexual reproduction?

meiosis = gametes

mitosis = somatic cells