Prophase
Prometaphase
Metaphase
Anaphase
Telophase & Cytokinesis
100

Where does Prophase come in the order of mitosis?

It is the first step in mitosis and comes before Prometaphase.

100

What stage is prometphase?

The second stage

100

True or False: Sister chromatids separate and move to opposite ends of the cell.

False; this happens in anaphase.  In metaphase, chromosomes line up at the metaphase plate.

100

During Anaphase, which structures are pulled toward opposite ends of the cell?

Sister chromatids

100

What is formed during this phase?

Daughter nuclei

200

True or False: Centrosomes move towards each other

False; centrosomes move away from each other.

200

True or False: Microtubules enter the cytoplasm and some attach to kinetochores.

False; microtubules enter the NUCLEAR AREA and some attach to kinetochores.

200

Chromosomes are at _____ poles.

Opposite

200

 What happens to the cell?

The cell elongates

200

What reappears during this phase?

Nucleoli

300

What begins to form during prophase?

Mitotic spindles

300

What happens in prometaphase?

The nuclear envelope fragments and the mirotubules enter nuclear area.

300

True or False: Chromatids have not separated yet in metaphase.

True

300

Why do sister chromatids move to opposite ends of the cell?

Due to the microtubules shortening

300

What happens to chromosomes?

They become less condensed

400

What are the mitotic spindles made of?

Microtubules 

400

How does the breakdown of the nuclear envelope during prometaphase facilitate mitosis?

The breakdown of the nuclear envelope allows spindle fibers to access the chromosomes.  This access is necessary for microtubules to attach to the kinetochores.  Without this breakdown, chromosomes would remain trapped inside the nucleus and the cell would not proceed with mitosis.

400

What happens if the microtubules don’t properly attach to the kinetochore?

The daughter cells might have an uneven number of chromosomes, leading to a genetic imbalance that can lead to many diseases.

400

 What are microtubules?

Tubular structure present in numbers in the cytoplasm of cells

400

How does cytokinesis occur in plant cells?

Vesicles produced by the golgi travel to the middle of the cell and form a cell plate

500

Chromatin condenses during prophase.  What is chromatin?

Strings of nuclesomes

500

What cellular structures are involved in the process of breaking down the nuclear envelope?

The nuclear envelope disassembly is regulated by CDKs, which phosphorylate nuclear lamins (the target proteins) to break down the structure.

500

Draw what metaphase looks like in a cell

500

What checkpoint would the cell have to go through before continuing to anaphase?

M (spindle) checkpoint

500

How does cytokinesis occur in animal cells? 

A cleavage furrow appears due to a contractile ring of actin filaments