Therapeutic Action
Mitotic inhibitors are cell cycle-specific, meaning they work during this part of the cell cycle.
mitosis
Patients with issues in these two organs should use mitotic inhibitors with caution due to metabolism and excretion concerns.
liver and kidneys
When an IV line with mitotic inhibitors leaks outside the vein, it can lead to complications.
Extravasation
Mitotic inhibitors should be used with caution if combined with other drugs that are toxic to this major organ and this system
Liver and CNS
This is the type of cancer for which mitotic inhibitors are often prescribed.
tumors and leukemias
A mitotic inhibitor poses an extra risk for patients with a prolonged QT interval, a heart condition related to electrical activity
Eribulin
Patients on mitotic inhibitors may experience toxicity in these two organs, requiring regular monitoring.
liver (hepatic) and kidneys (renal)