The Rh Blood Group System
Common Blood Group Systems
Fundamentals of Immunology and Basic Immunogenetics
The ABO Blood Group System
Uncommon Blood Group Systems
100
Biochemically speaking, Rh antigens are composed of:
What are proteins?
100
This abnormal red cell morphology is observed in patient's of the McLeod phenotype.
What are acanthocytes?
100
This cell type is responsible for the production and secretion of immunoglobulins.
What are B cells/ Plasma cells?
100
This man is credited with the discovery of ABO blood groups in 1901.
Karl Landsteiner
100
This antigen is poorly expressed at birth and may not demonstrate until 7 years of age.
What is the P1 antigen?
200
Persons lacking all Rh antigens are said to belong to this phenotype.
What is Rh null?
200
The gene which codes for the expression of Kell antigens is located on this chromosome.
What is chromosome 7?
200
The electrical charge of in the ionic cloud which surrounds each RBC.
What is negative? Zeta potential
200
Person's who inherit genes coding for the addition of N-acetyl-galactosamine to the type 2 chains on their RBCs belong to which ABO blood group.
What is A, blood group A?
200
The antigens in this blood group system are composed of branched carbohydrate structures and are developmentally related.
What is blood group I?
300
This Rh nomenclature system is based upon the (incorrect) theory that a single gene controls Rh expression.
What is Wiener nomenclature?
300
This blood group system includes antigens carried on glycophorin proteins, and its antibodies may show dosage and are sometimes associated with enzyme-sensitive reactions.
What is MNSs?
300
This process refers to the coating of RBCs with antibody.
What is sensitization?
300
Secretor testing on an individual reveals the presence of soluble A and H antigens. This person belongs to blood goup:
What is A, blood type A?
300
This blood group system contains three antigens, is associated with naturally occurring antibodies and plays a role in paroxysmal cold hemoglobinuria.
What is the P blood group system?
400
This gene, present on chromosome 6, is required for expression of Rh antigens.
What is the Rh Associated Glycoprotien (RHAG)
400
Persons lacking antigens of this blood group system are said to have natural resistance against certain plasmodium infections.
What is Duffy?
400
The ABO and Rh blood group systems follow which type of inheritance pattern.
What is codominant?
400
The presence of deacetylase enzymes could interfere with test results for this ABO antigen.
What is B, blood group B?
400
This blood group system contains only 2 antigens. One of which is CD99.
What is the Xg blood group system?
500
Presence of this antigen, belonging to the Rh blood group system, is the result of a single amino acid change in the RHCE gene.
What is the Cw antigen?
500
This blood group system’s antigens are not intrinsic to the RBC membrane but are instead passively adsorbed from plasma glycolipids.
What is Lewis?
500
In classical complement activation, C1q complex binds to which region of the immunoglobulin.
What is the Fc region?
500
This chromosome is home to the genes which control the expression of ABO genes
What is chromosome 9?
(H and Se genes are on ch 19)
500
Antigens of this blood group system exist on C4 molecules before being adsorbed to the red cell membrane.
What is the Chido Rodgers blood group system?