Unit 1
What immunoglobulin class reacts best in the antiglobulin testing?
IgG
Anti-D can react stronger with:
R2R2 cells
What is the immunoglobulin class of antibodies detected in the immediate spin crossmatch?
IgM
For patients receiving autologous units, which part of the compatibility procedure is not required?
Antibody screen
What is the minimum acceptable storage temperature for frozen red blood cells?
-65 degrees C
Where can you locate information regarding reagent limitations?
Product inserts
How is it genetically possible for a child to phenotype as D-negative?
Both parents are homozygous D positive
How long following a transfusion must the receipts sample be stored?
7 days
What type of HDFN affects the first born?
ABO
How often can a person donate a unit of whole blood for a directed donation?
8 weeks
What term is responsible for the activation of the classic pathway of complement?
Antibody body to antigen
Which donor red cells are compatible for a patient with Bombay (Oh) Phenotype?
Bombay (Oh) only
Mixed field reactions can be observed in what methodology?
Gel column agglutination
Rh immune globulin contains:
IgG Anti-D
How long must a donor wait to donate red blood cells again following a 2 unit red blood cell apheresis donatation?
16 weeks
The children of a Group AB mother and Group B father could have which phenotype?
O
Transfusion reactions due to Rh blood group system antibodies typically cause:
Extravascular hemolysis
What is likely the consequences of forgetting to incubate the gel card prior to centrifugation?
False negative
What is the cause of post transfusion purpura?
Platelet antibodies
Allogeneic whole blood donors may donate every ____ days
56
When the individual is blood group A, what is the term that applies?
Phenotype
What is the percentage of the population are secretors (express Se gene to produce H substance in saliva)?
80%
Which blood group systems has been implicated in transfusion reactions on the first exposure to incompatible red blood cells?
ABO
A 300 ug dose of Rh immune globulin contains sufficient Anti-D to protect against how much whole blood?
30 mL
What is the most effective component to treat a patient with von Willebrand disease?
Cryoprecipitate AHF