Membrane Potential
Cell Structures
The CNS
The eyes
The ears
100

What has the greatest effect on the resting membrane potential?

K+ concentration

100

Gaucher's disease involves the accumulation of macromolecules within a cell. What organelle is most likely at fault?

Lysosomes

100
Significant damage to the dorsal root ganglion would cause what?

loss of sensory information from that side

100
Cone dystrophy would likely cause what symptoms?

loss of color vision

100

An otolith is dislodged and floating around in the ear. Where should it return to?

The vestibule

200
A mutation in the gene coding for the Na/K pump would most likely lead to what?

inability to maintain resting membrane potential

200

Microglia most likely have a lot of which organelle?

lysosomes

200

Which cellular structure/shape would you expect ependymal cells to be?

Simple cuboidal

200

What time of day would someone with cone dystrophy be able to see the best?

Dusk
200

A physician looks into the external auditory canal. What is the innermost structure that they see?

tympanic membrane

300

What causes the depolarization phase of an action potential?

reaching threshold from a summation of graded potentials

300

What is a major protein of the cell junction that facilitates fast and synchronous communication among cells?

connexins

300

Damage to the cerebellum would cause loss of what motor function?

coordination

300
What is the path light travels as it moves through the retina?

ganglion cell-amacrine cell-bipolar cell-horizontal cell-photoreceptor

300

What is the function of the ossicles?

Amplify vibrations

400

A toxin blocking K+ channels would have what affect on resting membrane potential?

the potential would become depolarized as K+ permeability decreases.

400

The cell junction type using occludins and claudins is what?

tight junctions
400

Why is neuronal impairment a symptom of demyelinating disorders?

There is a decrease in AP transmission velocity, delaying NT release

400

Which photoreceptor is used in low light situations?

Rods

400

How does a sound wave travel through the ossicle bones?

malleus-incus-stapes

500
A neuron has a membrane potential of +15 mV. This neuron is most likely...?

propagating an action potential

500

What cell junction uses cadherins?

Adherens junctions

500

To bypass the blood-brain barrier, a drug should alter what aspect of the barrier?

interrupt tight junctions of astrocytes

500

Which bipolar cell is activated when there is light present?

On bipolar cells

500

How do hair cells get depolarized?

Mechanical stimulation