In 2024, Demis Hassanabis and John Jumper won half of the Chem Nobel for AlphaFold, while the other half was won by this Husky scientist for novel protein design using computation
Who is David Baker
This city, which shares its name with the UChicago mascot, is located in the middle of the desert
What is Phoenix (Ray)
This person has hit a home run on an MLB field
Who is Ray
These two buildings are the tallest in Chicago
What is the Willis Tower and the Trump International Hotel and Tower?
It is Christmas tradition for a couple to kiss under this plant
What is the mistletoe
Wildfires swept through this major metropolitan area in January, causing the worst damage in the state's history
What is Los Angeles
The 1950 Nobel was awarded to these two scientists for the "discovery and development of the diene synthesis"
Who are Diels and Alder
This city is the capital of e-sports, boasting numerous professional teams and dedicated e-sports arenas
What is Seoul (Sooin)
This person has been to a taping of CBS's late night show (The Colbert Show). The guest: Kamala Harris
Who is Guna
This invention, designed to rotate in a circular motion with passengers and is often an tourist attraction, was first built for the 1893 World's Fair in Chicago
What is the Ferris wheel?
This movie features Will Ferrell as a human raised by Santa's workers trying to find his real father
What is 'Elf'
This man, born in Joliet and a noted White Sox fan, was made the pope of the Catholic Church in May, making him the first American-born pope
Who is (either) Leo XIV or Robert Prevost
For the development of click chemistry and bioorthogonal chemistry, the 2022 Nobel was awarded to these three scientists (need all 3)
What is Sharpless, Meldal, and Bertozzi
This city has the world's largest metro system and the most number of coffee shops in the world
What is Shanghai (Scarlett)
This person was in a break dance crew when they were in undergrad
Who is Sooin
One of the most famous paintings in the Art Institute depicts an older couple, with the man holding a pitchfork, and a white house behind them; this happens to be a very recognizable piece of Americana
What is 'American Gothic'

This seasonal drink, made of beaten eggs, cream, and milk (often mixed with alcohol) was the cause of a riot at West Point in 1826
What is eggnog
This 95-year-old based in Omaha said that he would step down as CEO of Berkshire Hathaway by the end of this year
Who is Warren Buffett
As one of five individuals with 2 Nobel Prizes, Frederick Sanger won his for these two breakthroughs
1. protein structure (insulin)
2. first DNA sequencing
This city has the world's oldest polo club and the largest literary festival in the world
What is Kolkata (Pratyasha)
This person has crocheted huge mushrooms and octopi
Who is Scarlett

This historic route, also known as the "Mother Road," used to go from Chicago to Los Angeles. It starts right in front of the Art Institute
What is Route 66
Who is Krampus
This Chinese answer to OpenAI's ChatGPT caused the largest drop in value for a single company (Nvidia) in US stock market history
What is DeepSeek
The Nobel in 2016 centered these types of organic molecules capable of movement and controlled by external stimuli like light, heat, or electricity, an example of which is below

What are "molecular machines"

What is Columbus (Mason)
This person participated in a 178-mile team relay race, running the anchor leg that ended at a bar called The Bucket of Blood Saloon
Who is Somayeh
This catchphrase, popularized by Saturday Night Live, captures the city's loyalty to its sports teams; specifically, its most ursine team
What is "Da Bears"
This Scottish song is typically sung at the stroke of midnight on New Year's Day to bid farewell to the old year
What is 'Auld Lang Syne'
A recent report shows that this Southeast Asian capital city has surpassed Tokyo to be the most populous in the world
What is Jakarta