Which natural cancer medication is associated with dose dependent cardiotoxicity
Bonus: what is the medication given to reverse/prevent cardiotoxicity
Doxorubicin
Bonus: Dexrazoxane
Name 3 disease/disorders that can cause Genu Varum
Blount's disease, Rickets, achondroplasia
The age at which a baby should be able to run
18 months
The most common classification of cerebral palsy
Spastic
6-mercaptopurine, 6-thioguanine
Name two classic metaphyseal lesions that are associated with abuse in non-ambulatory patients
Bonus: What types of motions would typically cause this?
Bucket handle fracture, metaphyseal bone collar
Bonus: Shearing forces (ie pulling, twisting)
A 47 Yo Cancer patient presents to the clinic with hand and foot pain. PE reveals erythematous desquamation of both the hands and feet. What cancer medication is the patient taking that likely causes his sxs?
A 3 Yo patient presents to the clinic with back pain and refusal to walk. PE notes that patient has fever of 101.4, and is sitting very straight, with refusal to bend their middle back. Hx reveals that patient had a scratch on his hand a few weeks ago, but that has since healed. What is the most likely cause of the sxs?
Osteomyelitis secondary to S. aureus infection
Gower's sign is indicative of weakness of which muscles
Proximal leg muscles (also evident in dermatomyositis, polymyositis)
Legg-calve-perthe disease presents with this type of limp:
The part of a meniscus that is most likely to heal on its own without surgical intervention:
Out portion (more blood supply)
Causes of cerebral palsy that can happen after birth
head trauma, meningitis
Screen for developemental dysplasia of the hip at this age.
What imaging modality is typically during this screening?
6 weeks
US
If a cancer patient has previously been dx'd with Leisch Neyhan syndrome, why can you not give them 6-MP or 6-TG
If a kid with Down's syndrome wants to play a sport, they should be screened for this prior to starting:
Atlanto-axial instability
Two anti-cancer drugs that operate by binding to tubulin monomers
Bonus: What hyponatremic causing side effect can manifest as a result of taking this medication
Vincristine, Vinblastin
Bonus: SIADH
The only complete patellar fracture that does not result in loss of knee extension
vertical fracture
Lab tests you can do when checking for DMD
Serum CK, Dystrophin Western blot
Treatment for an isolated fibular head fracture
non-surgical (ie splinting, crutches)
Dx of cerebral palsy requires that isn't hitting motor milestones and any of the following:
Hypertonia, hypotonia, asymmetric movement
Describe the position used for the McMurray's test when checking for medial meniscus injuries
Foot externally rotates and valgus force applied to knee. Move knee from full flexion to extension
A 13 year old patient presents with heel pain while running, but it is better at rest. PE reveals pain to palpation of the posterior calcaneous. What is the most likely Dx
Sever disease (microfracture of calcaneal growth plate)
Plant and pivot, excessive valgus force, Excessive internal tibial rotation
A key way to differential between OI and child abuse is to look for this:
retinal hemorrhages
A patient comes into the ED following an MVA. They have c/o knee pain, and state that their knee "jammed" into the dashboard when the accident occurred. Radiographs reveal no bony abnormalities, but PE reveals positive Posterior drawer test. What is the likely diagnosis
PCL injury