Mechanism of Action
This neurotransmitter normally causes skeletal muscle contraction at the neuromuscular junction.
Answer: Acetylcholine
This life-threatening complication can occur if baclofen is stopped abruptly.
Answer: Seizures / rebound spasticity
Patients taking bisphosphonates must remain in this position for at least 30 minutes after taking the medication.
Answer: Upright / sitting or standing
A patient with MS spasticity affecting one limb may benefit most from this medication.
Answer: OnabotulinumtoxinA
A patient with MS spasticity has difficulty walking due to muscle stiffness. Which drug class should the nurse expect the provider to prescribe first?
Answer: Centrally acting muscle relaxants (e.g., baclofen)
Which cells build bone?
Answer: Osteoblasts
This medication treats focal spasticity by preventing acetylcholine release from nerve terminals.
Answer: OnabotulinumtoxinA
This major adverse effect must be monitored in patients taking dantrolene.
Answer: Hepatotoxicity
Before administering denosumab, the nurse should check this laboratory value.
Answer: Calcium
A patient with osteoporosis and severe GERD should avoid this medication.
Answer: Alendronate (bisphosphonate)
A patient with osteoporosis is prescribed alendronate. Which instruction is most important?
Answer: Take with a full glass of water and remain upright 30 minutes.
Which cells break down bone?
Answer: Osteoclasts
This drug works directly on skeletal muscle by blocking calcium release from the sarcoplasmic reticulum.
Answer: Dantrolene
Patients taking denosumab are at risk for this electrolyte abnormality.
Answer: Hypocalcemia
Patients taking diazepam for spasticity should be monitored for this respiratory complication.
Answer: Respiratory depression
Which drug class is considered first-line therapy for osteoporosis?
Answer: Bisphosphonates
A patient receiving denosumab reports muscle cramps and tingling. Which complication should the nurse suspect?
Answer: Hypocalcemia
What diagnostic test measures bone mineral density?
Answer: DEXA scan
This drug reduces spasticity by stimulating alpha-2 receptors in the spinal cord.
Answer: Tizanidine
This osteoporosis medication increases the risk of deep vein thrombosis.
Answer: Raloxifene
Which laboratory tests should be monitored in patients taking dantrolene?
Answer: Liver enzymes (AST/ALT)
A patient with severe osteoporosis and multiple fractures may be prescribed this bone-forming medication.
Answer: Teriparatide
A patient receiving diazepam becomes extremely drowsy and has a respiratory rate of 8/min. What is the priority action?
Answer: Assess airway and respiratory status
Which osteoporosis medication mimics estrogen effects in bone?
Answer: Raloxifene
This osteoporosis drug stimulates osteoblasts to build bone.
Answer: Teriparatide
This adverse effect can occur after onabotulinumtoxinA injections and requires immediate reporting.
Answer: Difficulty swallowing (dysphagia) or respiratory weakness
A patient taking cyclobenzaprine reports dizziness. What safety intervention should the nurse implement?
Answer: Fall precautions
A patient receiving succinylcholine develops muscle rigidity and high fever. Which drug treats this complication?
Answer: Dantrolene
A patient receiving botox injections for spasticity develops hoarseness and difficulty swallowing. What is the nurse’s priority response?
Answer: Notify provider immediately and assess airway.
Which drug class treats Paget’s disease by inhibiting osteoclasts?
Answer: Bisphosphonates