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Diagnosis
Pathophys
Management
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100

The name of the diagnostic criteria that is the gold standard for MS diagnosis.

Mcdonald critera.

100

The main target of auto immune destruction in MS.

myelin sheath proteins

100

What drug is given in high doses in hospital to control an acute attack?

Methylprednisolone

100

The most common gender and age demographic at time on diagnosis.

Females, 25-35

200

Autoantibodies produced by B cells that have crossed the blood brain barrier can be detected in CSF in this format.

Oligoclonal bands

200

Possible triggers of MS.

Virus/bacterium/environmental toxin

200

Other than immune therapy and corticosteroids, what treatment should be considered in MS?

Symptom management eg pain management

200

Common environmental risk factors

Latitude, Vitamin D deficiency, low UV

300

Chronic lesions are described as appearing like what on MRI.

Blackholes.

300

Name 2 common sites of MS lesion

Periventricular white matter (Dawson’s fingers), Corpus callosum, Pons, Medulla, Cerebellar white matter, Spinal cord, Optic nerve

300

Name some side effects of high dose short term use of methylprednisolone.

  • Mood and behavior shifts: Agitation, anxiety, confusion, or a false sense of well-being.
  • Sleep problems: Trouble falling or staying asleep (insomnia).
  • Metabolic changes: Spikes in blood sugar levels and increased appetite.
  • Physical signs: Facial flushing, metallic taste, and water retention.
  • Stomach distress: Nausea, heartburn, or risk of ulcers.
300

What is the most common type of MS out of primary progressive, relapsing-remitting, progressive relapsing and secondary progressive? Bonus points for the percentage.

Relapsing remitting. 80%