Muscle Anatomy
Sarcomere and Sliding Filaments
Excitation-Contraction and NMJ
Muscle Mechanics
Muscle Fatigue and Fiber Types
100

This dense fibrous connective tissue sheath wraps around the entire muscle belly and anchors it to bones via tendons

What is Epimysium

100

Bounded by adjacent Z-lines, this repeating segment is the smallest functional contractile unit of a muscle fiber

What is the Sarcomere?

100

This specific neurotransmitter is stored in synaptic vesicles and released by alpha motor neurons to stimulate skeletal muscle fibers

What is Acetylcholine

100

In this variety of isotonic contraction, the tension developed by the muscle exceeds the opposing resistance, resulting in muscle shortening

What is a concentric contraction?

100

During the first 10 to 15 seconds of explosive exercise, ATP is rapidly regenerated by transferring a phosphate group from this stored molecule to ADP

What is creatine phosphate?

200

In musculoskeletal anatomy, this term designates a muscle's proximal attachment point, while the distal attachment is the insertion

What is Origin

200

According to the sliding filament model, this dark band representing the full span of the thick filaments does not change length during contraction

What is the A band?

200

Synaptic signaling at the neuromuscular junction is swiftly halted when this enzyme degrades acetylcholine within the synaptic cleft

What is acetylcholinesterase

200

Exemplified by an arm-wrestling stalemate, this type of muscle action generates tension without altering the muscle's length

What is an isometric contraction?

200

Possessing high myoglobin content, high capillary density, and slow contraction speeds, these red fibers are built for prolonged endurance

What are Type I fibers. (slow twitch oxidative fibers)

300

Described as resembling "pearls on a string," these thin myofilaments are formed by the polymerization of globular G-actin monomers into F-actin strands

What are actin filaments (or thin filaments)?

300

Located at the center of the A band, this lighter region contains only thick myosin filaments and shortens or disappears as thin filaments slide inward

What is the H-zone?

300

The most common form of exhaustion, this fatigue originates within the cerebral cortex when the psychological drive to continue work is lost

What is psychological fatigue (or central command fatigue)?

400

These continuous invaginations of the sarcolemma conduct action potentials rapidly from the cell surface deep into the interior of the muscle fiber

What are transverse tubules?

400

To expose myosin-binding sites on actin, calcium ions released into the sarcoplasm bind directly to this regulatory protein complex

What is troponin C?

400

This mechanism causes allows the release of Ca2+ from the terminal cisternae.

What is concentration gradient.(Chemical gradient)
400

When stimulation frequency is so high that muscle fibers have no opportunity to relax between impulses, tension peaks in this smooth, sustained contraction

What is complete tetanus (or fused tetanus)

400

Lactic acid is converted back into this after being produced in the muscles after exercising. 

What is pyruvate?

500

In skeletal muscle microstructure, this functional trio consists of a single central T-tubule flanked on both sides by the terminal cisternae of the sarcoplasmic reticulum

What is a triad?

500

Following death, cellular ATP depletion prevents myosin heads from detaching from actin filaments, causing this state of muscle rigidity

What is rigor mortis?

500

This receceptor accepts the neurotransmitter acetylcholine on the motor end plate to start an action potential on the skeletal muscle

What is a Nicotinic receptor?

500

Delayed-onset muscle soreness (DOMS), which typically lasts 3 to 4 days, is triggered most intensely by this type of contraction where the muscle lengthens under load

What are eccentric contractions?

500

While Type IIa fibers can adapt toward Type IIx or Type I profiles depending on training, this specific fiber-type transition does not occur

What is a transition from Type I to Type II?