Mutations!

Definitions.

100

This is a good,bad or no change in a DNA sequence.

What is a mutation

200

What type of mutation causes the entire sequence after that to be altered? 

What is frameshift?

300

What mutation has the twice amount of chromosomes.

What is duplication mutation

400

Identify 2 examples of genetic diseases caused by mutations that we learned about.

What is Sickle cell, diabetes, cystic fibrosis, muscular dystrophy 

500

True or False. Mutations can be caused by various factors, including spontaneous errors during DNA replication, exposure to mutagens (chemicals or radiation), or other environmental factors.

True

Point Mutation

100

AUG-CUC-UUG -> AUG-CUA-CUU-GA What mutation is shown here??

What is an insertion mutation or What is an insertion frameshift mutation?

200

AUG-CUC-GUA-ACC -> AUG-CUC-GAA-CC What mutation is shown here?

What is a deletion mutation

300

CGA-AAU-CUC-CCC -> CGU-AAU-CUC-CCC (Codon chart needed) What mutation is shown here?

What is a silent mutation

400

What are the 3 point mutations?

Substitution, Insertion and Deletion

500

What type of mutation is this?

Normal      AAA ATG CTT CTC

Mutated     AAA ATG TTT CTC

Substitution

Mutations

100

All mutations are bad. True or False

False

200

AUC-GGA-ACA-CGU What DNA sequence would match this RNA sequence? a)TAG-CCT-TGT-GCT b)UCG-TGT-CCT-GAT c)TAG-CCT-TGT-GCU d)TCU-TAG-CGU-GCG

A)TAG-CCT-TGT-GCU

300

What effect does a Silent Mutation have?

No effect. Still codes for the same amino acid. 

400

Whats the difference between a point mutation and a frames shift?

A point mutation changes a particular spot of the DNA, While frame shift moves the DNA forward or backward.

500

Would a missense muation be part of- a)Point Mutation b)Gene Mutation c)Frame shift d)Chromosome mutation

What is a)Point Mutation

Logic Mutation Questions

100

If the mRNA sequence has a stop codon placed in the beginning of it what will happen? 

a)Sequence will not be affected 

b)sequence will have to recombine mRNA and DNA 

c)Arganine will be the next protein 

d)The sequence will be short and messed up

d)The sequence will be short and messed up

200

If an insertion mutation occurs what part of the sequence will be affected? 

a)Nothing will be affected 

b)The sequence before the insertion 

c)The entire sequence 

d)Where the insertion happened

d)Where the insertion happened (also after)

300

If the sequence AUC-GUG-CGU-ACA is changed to AUC-GAC ACA GCU- what will the new sequence code for?

a)Iso-Asp-Ther-Ala

b)Iso-Hist-Ther-Ala

c)Iso-Asp-Ther-Alg

d)Iso-Arg-Ther-Ala

 a)Iso-Asp-Ther-Ala

400

What type of mutations are frameshift mutations?

Insertion and Deletion

500

Substitution is what type of mutation? Frameshift, Point or Silent?

Point mutation