Mutations!

Mutation Definitions

100

This is a good,bad or no change in a DNA sequence.

What is a mutation

200

All mutations are bad. True or False

False

300

True or False: Mutations are only caused by mutagens (chemicals or radiation) and do not occur spontaneously.

False

400

What genetic blood disorder is caused by a single amino acid substitution?

Sickle cell anemia

500

What are the 3 point mutations?

Substitution, Insertion and Deletion

Name That Mutation!

100

Describe the mutation below:

Normal      AAA AUG CUU CUC

Mutated     AAA AUG UUU CUC

Point, substitution, missense

200

Describe the mutation below:

Normal      AUG-CUC-GUA-ACC 

Mutated     AUG-CUC-GAA-CCC

Deletion, frameshift, missense

300

Describe the mutation below:

Normal      AUG-CUC-GAA-CCC

Mutated     AUG-CUC-GAA-CCG

Substitution, point, silent

400

Describe the mutation below:

Normal      AAA AUG CUU UAC

Mutated     AAA AUG UUU UAA

Point, substitution, silent

500

Describe the mutation below:

Normal      AAA AUG CUU CUC

Mutated     AAA AUU CUU CUC

Substitution, point, nonsense

Mutation Types

100

What type of mutation causes the entire sequence after that to be altered? 

What is frameshift?

200

AUC-GGA-ACA-CGU What DNA sequence would match this RNA sequence? a)TAG-CCT-TGT-GCT b)UCG-TGT-CCT-GAT c)TAG-CCT-TGT-GCU d)TCU-TAG-CGU-GCG

A)TAG-CCT-TGT-GCU

300

What effect does a Silent Mutation have?

No effect. Still codes for the same amino acid. 

400

Whats the difference between a point mutation and a frames shift?

A point mutation changes a particular spot of the DNA, While frame shift moves the DNA forward or backward.

500

Would a missense muation be part of- a)Point Mutation b)Gene Mutation c)Frame shift d)Chromosome mutation

What is a)Point Mutation

Logic Mutation Questions

100

If the mRNA sequence has a stop codon placed in the beginning of it what will happen? 

a)Sequence will not be affected 

b)sequence will have to recombine mRNA and DNA 

c)Arganine will be the next protein 

d)The sequence will be short and messed up

d)The sequence will be short and messed up

200

If an insertion mutation occurs what part of the sequence will be affected? 

a)Nothing will be affected 

b)The sequence before the insertion 

c)The entire sequence 

d)Where the insertion happened

d)Where the insertion happened

300

If the sequence AUC-GUG-CGU-ACA is changed to AUC-GAC ACA GCU- what will the new sequence code for?

a)Iso-Asp-Ther-Ala

b)Iso-Hist-Ther-Ala

c)Iso-Asp-Ther-Alg

d)Iso-Arg-Ther-Ala

 a)Iso-Asp-Ther-Ala

400

What type of mutations are frameshift mutations?

Insertion and Deletion

500

Substitution is what type of mutation? Frameshift, Point or Silent?

Point mutation