Change in the DNA sequence that ranges in size and severity
What is Mutation
100
Mutation that causes malformation in hands or feet.
What is Ectrodactyly
100
Most common genetic condition
What is down syndrome
100
Bone marrow and stem cell transplants are possible treatments for this mutation
What is Bubble Boy Disease
100
Warts usually develop sometime during childhood
What is Epidermodysplasia Verruciformis
(TREE MAN)
200
Makes a copy of the chromosome but the copy flips so the letters don’t pair correctly
What is Inversion
200
Symptoms of this mutations include small jaw, below avg height & weight, short stature, pear shaped chest, hair loss, stiffness of various joints, prominent veins and eyes
What is progeria
200
What chromosome is affected in down syndrome.
What is 21
200
Prosthetic hands is a possible treatment for this mutation
What is Ectrodactyly
200
Mutation with life expectancy: 7 - Early 20’s (Avg. age is 13)
What is progeria
300
An example of this is “Strand slippage” the parent strand and daughter strand slip past each other and the bond is not normal
What is Spontaneous Mutation
300
“lobster claw” syndrome
Ectrodactyly
300
Common Characteristics of down syndrome
What is low muscle tone, small stature, upward slant to the eyes and a single deep crease across the center of the palm.
300
Main diseases being researched for gene therapy
What is cystic fibrosis, sickle cell anemia, hemophelia, cancer, and muscular dystrophy
300
Fewer than 250 children diagnosed
What is progeria
400
Not losing one letter, but losing a big portion of chromosome- hundreds or thousands
What is Deletion
400
Thick visible warts on body are a symptom to this mutation
What is Epidermodysplasia Verruciformis or tree man disease
400
Name 5 common Mutations
What is What is What is Freckles
Multicolored eyes
Red hair
Cleft chin
”No show” wisdom teeth
Color Blindness
Genetic Deafness
Lactose Tolerance
400
If this treatment is successful a functional protein will be created.
What is gene therapy
400
Inherited by the x chromosome, passed on my the mother.
What is SCID
500
An example of this is when exposure to radiation develops skin cancer
What is Induced Mutation
500
Caused by a random mutation in the gene called LMNA
What is progeria.
500
"Father" of Down Syndrome
John Down
500
Teaching early on how to adapt to everyday hand functions will help this mutation
What is Ectrodactyly
500
Name the 4 Teenage Mutant Ninja Turtles
What is Leonardo, Michaelangelo, Donatelo, and Rafael.