Leukocyte Pools
Periperal blood is in this pool.
What is Circulating pool.
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This cell is 12-18 um, round to oval nucleus, cytoplasm is a lighter blue with secondary granules
What are myelocytes
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White cells that function to produce antibodies.
What are B-lymphocytes or B-cells.
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Cells that perform phagocytosis.
Segmented neutrophils and monocytes (macrophages).
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These cells are also called polymorphonuclear neutrophils, or PMN's, and sometimes called stabs, using older terminology.
What are segmented neutrophils.
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This pool contains is where cells proliferate and undergo mitosis.
What is the mitotic pool.
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Plays a role in allergic reactions and parasitic infections by releasing histamine from its reddish-orange granules.
What are eosinophils.
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White cells that function to produce memory cells in response to viral antigens.
What are T-lymphocytes or T-cells.
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These small cells function to stop bleeding and seal up wounds, known as primary hemostasis.
Thrombocytes or platelets.
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These cells have a dark blue cytoplasm with an eccentric, round nucleus. A Golgi body, perinuclear clearing or halo may also be present. These cells are seen in the peripheral blood in multiple myeloma.
What are plasma cells or B-cells.
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Cells that live in the bone marrow reside in this pool.
What is the stem cell pool.
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Makes up 50-70% of normal granulocytes in the peripheral blood.
What are segmented neutrophils.
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A cell that can process certain foreign substances for immunity and clean up remnants phagocytosis. One of the garbage cans and recycle centers of the blood system.
What are macrophages.
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Another name for ecchymosis.
What is a bruise.
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Pinpoint purple or red spots on the skin or mucous membranes; indicates a systemic bleeding disorder.
What are petechiae.
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In this pool, granulocytes adhere to vessel walls before entering the circulating pool.
What is the marginating pool.
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This cell has a kidney-bean shaped nucleus with clumped chromatin, about 10-15um in size, and contains specific granules.
What are metamyelocytes.
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A large cell with a round, oval, convoluted, deeply indented, or horse-shoe-shaped nucleus with a lacy chromatin pattern. The cytoplasm commonly has vacuoles, due to its ability to help out with phagocytosis.
What is a monocyte.
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What are lysosomes.
Another name for platelet clusters that resemble a clot, when seen on a Wright's stained smear.
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This pool contains 4 additional pools within it: stem cell pool, mitotic pool, marginating pool and storage pool.
What is the Bone Marrow pool.
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This cell is 15-20um in size, has a round to oval nucleus with 2-4 visible nucleoli, a large nucleus with a small amount of cytoplasm (scant).
What are myeloblasts.
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The process that involves chemotaxis, adherence, engulfment, fusion, digestion and destruction, in that order.
What is phagocytosis.
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This cell requires alpha and delta granules, lysosomes, and dense tubular system to function to stop bleeding.
What are the functional units of platelets.
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The steps listed are a part of which stage hemostasis:
vasoconstriction, platelet adhesion, platelet aggregation, platelet plug formation, consolidation of platelets, fibrin stabilization
What is primary hemostasis.
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