Route
This route bypasses the GI tract
Parenteral
High-fat meals generally do this to absorption
Slow it
Liquids absorb faster than this
Tablets
Increased motility causes absorption to:
Decrease
T/F: OTC drugs can interact with prescriptions
True
This route has the fastest onset
IV
Best fluid to give meds with
Water
Enteric-coated tablets dissolve here
Intestine
Diarrhea does this to absorption
Decreases it
Weight loss products can affect absorption by:
Increasing transit time
Most oral drugs are absorbed here
Small intestine
Calcium-rich foods decrease absorption of this antibiotic
Tetracycline
This type releases slowly over time
Extended release
Slower transit time does what to absorption?
Increases absorption
Why must we ask about supplements?
Drug interactions
This oral route avoids first-pass metabolism
Sublingual
Exercise has what effect on GI absorption?
Decreases it
Crushing this tablet is dangerous
Extended release
Most surface area in GI tract is here
Small intestine
This route depends heavily on tissue blood flow
IM/SC
This juice interferes with liver enzymes and affects metabolism.
Grapefruit juice
Bowel resection leads to what related to absorption:
Reduced absorption