General NBOB
This is the amount of a drug present in the blood and available for interaction with a target
What is Bioavailability?
OXTR
What is the only known Oxytocin receptor?
ACh
What transmitter does nictoine mimic?
Shrooms, mushies, caps, blue meanies, silly putty
What are 5 street names for psilocybin mushrooms?
THC (tetrahydrocannabinol) and CBD (cannabidiol)
What are the two primary cannabinoids in cannabis?
In this experiment, neither the patient or the observer knows what treatment the participant has recieved.
What is a double-blind experiment
One of the potentially negative aspects of oxytocin administration, adding Oxytocin was shown to increase this when it was already present in the group.
What is xenophobia?
They are mostly presynaptic and modulatory in the brain, but postsynaptic in the NMJ.
Where are the locations of the nAChR in the periphery and the cortex?
5HT-2A
What receptor do psychedelics mainly act on?
2-AG and anadaminde
What are the two primary endogenous cannabinoids?
This is the extent to which the animal measurement tool actually measures the characteristic being investigated.
What is construct validity?
It encourages osteoblasts to build them bigger
What effect does Oxytocin have on bones?
Baseline dopaminergic and noradrenergic signaling in prefrontal circuits is often lower, so these individuals tend to seek stimuli that rapidly “bring them up” toward a functional baseline
Why would a less focused adolescent be more vulnerable to TUD?
Raphe Nuclei
Which brain structure is the primary structure responsible for releasing 5-HT?
impairment of hippocampal-dependent memory
blunted reward system responsivity (reduced striatal dopamine signaling),
anhedonia or motivational deficits i
What are three common outcomes of chronic cannabis use of cannabis?
A behavioral task that measures anxiety based on the amount of time spent in the open arms
What is the elevated plus maze?
A form of synthetic oxytocin, this drug is given to many women when they are giving birth, but nobody seems to be keeping track of how much!
What is pitocin?
These rats show an increase in alcohol consumption as adults
What is one thing that can happen to adolescent rats who are given nicotine?
Tryptophan
What essential amno acid is the prescursor for serotonin?
Beneficial in the short term, but may be harmful in the long term.
What does the current research say about cannabis and sleep?
As x increases, y increase too. This does not indicate causation.
What is a positive correlation?
10-12% of mothers suffer from this, and research suggests it is related to the changes in oxytocin surrounding pregnancy, birth, and nursing a child.
What is post-partum depression?
This cigarette has the most powerful effect because overnight abstinence allows nicotinic acetylcholine receptors to resensitize and dopamine baseline activity in the mesolimbic pathway to drop.
Why is the first cigarette of the day reliably judged to be the best by smokers?
a psychoactive compound derived from the African Tabernanthe iboga shrub
24 U.S. states and the District oc Columbia
How many states have legalized cannabis for recreational use?