Show:
Chronic Kidney Disease
Common Renal Dose Adjustments
Creatinine Clearance & GFR
Acute Kidney Injury
Dialysis
100
This is one of the most important vital signs to control at goal in order to help slow the rate of progression of chronic kidney disease.
What is blood pressure?
100
Antibiotics, antifungals, antivirals, metformin, sitagliptin, & enoxaparin are common _________ _________ ________ medications.
What is renal dose adjusted?
100
In the Cockcroft-Gault equation, this is the adjusted body weight equation for patients whose actual body weight is greater than or equal to 120% of their ideal body weight.
What is IBW + 0.4(Actual BW – IBW)?
100
Hypovolemia (vomiting, diarrhea, diuretic use, bleeding), hypotension, infection, and eGFR lowering drugs (such as NSAIDs, ACEIs), commonly cause _____________ in renal function.
What is decrease?
100
This drug is typically used to flush dialysis catheters to prevent the formation of clots.
What is heparin? LMWH and direct thrombin inhibitors can also be used systemically.
200
A creatinine clearance between 15-29 ml/min will put you in this stage of chronic kidney disease.
What is stage 4, severely reduced kidney function?
200
This is the general DVT prophylaxis enoxaparin dose for patients weighing 45-150 kg with a CrCl < 30 ml/min.
What is 30 mg SC daily?
200
These are some patient specific factors that may affect the accuracy of the estimated renal function.
What is dehydration, low muscle mass, trauma, burns, etc.?
200
Aminoglycoside antibiotics, NSAIDs, and radiographic contrast material are considered these kinds of drugs.
What is nephrotoxic?
200
Name one of the three major types of vascular accesses for maintenance hemodialysis.
What is arteriovenous (AV) fistulas, synthetic AV fistulas (AV grafts), and double-lumen, cuffed tunneled catheters?
300

This is the treatment of choice for patients with end stage renal disease.

What is kidney transplantation?

300
The normal dose for sitagliptan is 100 mg by mouth once daily in adults with normal renal function. This is the dose given in end-stage renal disease.
What is 25 mg once daily, regardless of hemodialysis timing?
300
This is the equation used to calculate creatinine clearance in pediatric populations (<18 years old).
What is the “Modified” Schwartz equation? GFR (ml/min/1.73 m2) = [0.413 x length (cm)] / Scr (mg/dL)1-2
300
Acute kidney injury is most commonly due to _________ _________ ________ (ATN) from ischemia, nephrotoxin exposure, or sepsis.
What is acute tubular necrosis?
300
An appropriate ceftazidime dose for treating meningitis in a patients on hemodialysis is 1g every __________ hours.
What is every 48 hours after dialysis?
400
In patients with chronic kidney disease, volume overload is managed with a daily dose of a loop diuretic and sodium intake is usually restricted to this amount per day
What is <2 g/day?
400
In general, hemodialysis will remove about this much percent of a vancomycin dose. Therefore, spot dosing is typically utilized in these patients.
What is 20-30%?
400
Because pregnant women tend to have a high calculated creatinine clearance, a SCr greater than this number may indicate kidney injury.
What is 1 mg/dl?
400
______phosphatemia and __________calcemia are commonly observed in patients with AKI.
What is hyperphosphatemia and hypocalcemia
400
These are general indications for dialysis in cases where they are not responsive to other treatments (AEIOU).
What is Acidosis, Electrolytes (hyperkalemia), Ingestions, Overload (fluid), Uremia (encephalopathy or pericarditis)?
500
The following are components of a common disorder associated with chronic kidney disease: abnormalities of calcium, phosphorus, parathyroid hormone, or vitamin D metabolism; abnormalities in bone turnover, mineralization, volume linear growth, or strength; and extraskeletal calcification.
What is chronic kidney disease-mineral and bone disorder (CKD-MBD) previously known as renal osteodystrophy?
500
The use of nitrofurantoin is avoided in patients with this creatinine clearance or below.
What is 40 ml/min?
500
These drugs interfere with either creatinine secretion or the assay used to measure the serum creatinine and will therefore appear to cause a false change in GFR.
What is cimetidine, dronedarone, trimethoprim, cefoxitin, and flucytosine?
500
These are the potentially life-threatening complications of AKI.
What are volume overload, hyperkalemia, acidosis, and uremia?
500
In continuous renal replacement therapy (CRRT), these drug specific characteristics/factors affect their dialyzability.
What is molecular weight, protein binding, volume of distribution, water solubility, and plasma clearance?