Neuro Meds
Med S/E
Priority + Meds
Diagnosis
Red Flags
100

A patient in status epilepticus is given a rapid IV medication that stops the seizure. The provider then orders a second medication to maintain seizure control. Name BOTH medications in correct order.

Lorazepam → then Phenytoin (or Levetiracetam)

  • Lorazepam: fast-acting benzo, stops seizure immediately
  • Phenytoin/Levetiracetam: longer-term seizure control
100

A patient receives lorazepam IV for a seizure. Within minutes, the patient becomes very drowsy and respirations drop to 10. What is the priority nursing action?

Support airway and prepare for ventilation

  • Lorazepam → causes respiratory depression
  • Airway ALWAYS priority before anything else
100

A patient begins actively seizing in bed. The provider has already ordered lorazepam IV, but it has not been given yet. What is the nurse’s FIRST action?

Turn the patient on their side and protect the airway

  • Airway > meds
  • Give lorazepam AFTER safety is established
100

A patient is given lorazepam IV, followed by phenytoin, after experiencing:

  • loss of consciousness
  • tonic stiffening
  • rhythmic jerking
  • postictal confusion

What is the diagnosis?

Tonic-clonic seizure

  • Clue: benzo → then maintenance anticonvulsant
100

A patient receives lorazepam IV for a seizure. Shortly after, respirations drop to 10 and the patient is difficult to arouse. What is the red flag and action?

Respiratory depression → support airway immediately

  • Benzos depress CNS
  • Airway > everything
200

A patient with increased ICP is receiving an osmotic diuretic. A few hours later, labs show rising serum osmolality and increasing creatinine. What medication is this, and what is the priority action?

Mannitol → HOLD and notify provider

  • Risk: kidney failure, fluid shifts
  • Nursing: monitor osmolality + renal function
200

A patient taking phenytoin presents with swollen, bleeding gums. What is the most appropriate nursing intervention?

Reinforce strict oral hygiene and regular dental care

  • Side effect: gingival hyperplasia
  • Not an emergency → focus on prevention/education
200

A patient arrives to the ED with stroke symptoms and is a potential candidate for alteplase. What is the FIRST priority before administering the medication?

Obtain a CT scan

  • Must determine ischemic vs hemorrhagic stroke
  • Giving tPA to hemorrhagic stroke = fatal
200

A patient receives alteplase after presenting with:

  • unilateral weakness
  • facial droop
  • slurred speech
  • symptom onset 1 hour ago

What condition is being treated?

Acute ischemic stroke

  • Clue: tPA = clot, not bleed
200

A patient receiving phenytoin IV develops hypotension and cardiac dysrhythmias during infusion. What is the red flag and action?

Cardiac instability → slow/stop infusion and monitor cardiac rhythm

  • Phenytoin IV must be given slowly
  • Risk: hypotension, arrhythmias
300

A patient with acute ischemic stroke receives a thrombolytic. Thirty minutes later, the patient develops a sudden severe headache, vomiting, and decreased LOC. What medication was given, and what is the complication?

Alteplase (or Tenecteplase) → hemorrhagic transformation

  • Risk: bleeding (BIGGEST)
  • Nursing: stop infusion, notify provider immediately
300

A patient is receiving levetiracetam and begins showing increased irritability, agitation, and mood swings. What is the best nursing action?

Monitor and report behavioral changes to provider

  • Side effect: mood/behavior changes
  • Can indicate need to adjust therapy
300

A patient with increased ICP is restless and trying to sit up and bend their neck forward. The provider has ordered mannitol, but it has not yet been administered. What is the nurse’s FIRST action?

Reposition head midline and elevate HOB 30°

  • Positioning immediately reduces ICP
  • Faster than waiting for medication effect
300

A patient with a head injury is receiving mannitol and becomes:

  • restless
  • confused
  • increasingly difficult to arouse

What condition is MOST likely occurring?

Increased intracranial pressure (ICP)

  • Clue: mannitol is used to treat ICP
300

A patient on mannitol now has:

  • decreasing urine output
  • rising creatinine
  • worsening confusion

What is the red flag and action?

Renal failure → hold medication and notify provider

  • Mannitol can worsen if kidneys aren’t functioning
400

A patient with spinal cord injury develops hypotension and bradycardia. The provider orders two medications: one to increase heart rate and one to increase blood pressure. Name BOTH medications.


Atropine (↑ HR) + Norepinephrine (↑ BP)

  • Atropine: treats bradycardia
  • Norepinephrine: vasopressor for hypotension
400

A patient receiving mannitol for ICP has the following changes: decreasing urine output, rising creatinine, and increasing confusion. What is the priority action?

Hold the medication and notify the provider immediately

  • Indicates renal failure / ineffective clearance
  • Mannitol can worsen condition if kidneys fail 
400

A patient with spinal cord injury develops hypotension and bradycardia. The provider orders norepinephrine and atropine. The medications are not yet available. What is the nurse’s FIRST action?

Initiate IV fluid bolus

  • Supports BP immediately
  • Meds come next
400

A patient with spinal cord injury is prescribed atropine and norepinephrine after developing:

  • hypotension
  • bradycardia
  • warm, dry skin

What condition is this?

Neurogenic shock

  • Clue: both meds used to fix HR + BP
400

A patient receives alteplase and 1 hour later develops:

  • sudden headache
  • vomiting
  • decreased LOC

What is the red flag and action?

Intracranial hemorrhage → STOP infusion immediately and notify provider

  • This is the most dangerous complication of tPA
500

A patient with TBI is receiving multiple medications:

  • One to reduce ICP
  • One to prevent seizures
  • One to control blood pressure

The patient becomes bradycardic, hypotensive, and has decreasing urine output. Which medication is MOST likely contributing to the current deterioration?

Mannitol

  • Causes fluid shifts → can lead to hypotension + renal impairment
  • Key clue: ↓ urine output + hemodynamic instability
500

A patient with ischemic stroke receives alteplase. Two hours later, the nurse notes:

  • Sudden headache
  • Vomiting
  • Decreased LOC

What is happening, and what is the nurse’s FIRST action?

Suspected intracranial hemorrhage → STOP infusion and notify provider immediately

  • Alteplase → major risk = bleeding
  • This is a medical emergency
500

A patient with TBI is receiving mannitol and levetiracetam. The nurse notes:

  • Decreasing LOC
  • O2 sat dropping
  • Increasing agitation

What is the nurse’s FIRST action?

Assess airway and provide oxygen

  • Airway ALWAYS priority
  • Even before adjusting meds or calling provider
500

A patient is receiving:

  • labetalol for BP control
  • alteplase for stroke

Suddenly develops:

  • severe headache
  • vomiting
  • decreased LOC

What is the MOST likely diagnosis?

Hemorrhagic transformation (intracranial bleed after tPA)

  • Clue: tPA + neuro decline = bleeding
500

A patient with spinal cord injury is receiving norepinephrine. The nurse notes:

  • BP rising appropriately
  • BUT extremities becoming cold and pale

What is the red flag and action?

Excessive vasoconstriction → assess perfusion and titrate medication

  • Risk: tissue ischemia
  • Balance BP vs perfusion