300
Unpredictable which signs (lower or upper) will predominate throughout course of disease
May be characterized by harsh, strained-strangled voice associated with low pitch,
wet, gurgly vocal quality present in some cases,
hypernasality,
imprecise consonant production and vowel distortions,
slow rate and range of movement of articulators
What is Amyotrophic lateral sclerosis (ALS)?
FYI: This is mixed upper and lower motor neuron, which involves the progressive degeneration of the neurons of the upper and lower motor neuron systems; the etiology is unknown.