Epilepsy
Which AED most commonly causes hyponatremia
Carbamazepine or Oxcarbamazepine
Which artery causes head of caudate infarct?
Recurrent artery of Huebner
Mechanism of action of Fingolimod
Downregulation of S1P- decreases egression of lymphocytes from lymphoid tissues
Gene involved in Dravet's syndrome (Severe myoclonic epilepsy of infancy)
SCN1A
Finger drop- what nerve & where is the level of lesion
PIN at radial tunnel
What is the diagnosis- Video?
Facio-brachial dystonia; LGI1
What are the symptoms caused by stroke in this artery on the dominant side? (Picture attached)
Gerstmann syndrome- dyscalculia, finger agnosia, dysgraphia, and right-left confusion
28 year old lady presents with L eye vision loss. MRI brain shows this. What is the diagnosis?
NMO
Why did this patient come to neurologist for?
Seizures- Tuberous sclerosis
44 year old lady with 3 month history of myalgia, difficulty climbing stairs, and difficulty swallowing. Her skin examination showed this.
Dermatomyositis
18 year old woman with abnormal behavior, drowsiness and abnormal movements of her extremities. EEG shows this.
Delta brush pattern in NMDA encephalitis
42 year old gentleman with short term memory issues presents with sudden onset L sided weakness. His MRI shows this.
CADASIL
54 year old with rheumatoid arthritis on treatment presents with L sided sensory symptoms and weakness over 3 week duration.
PML
Progressive aphasia in toddler of 4 years of age. EEG shows this.
Landau-Kleffner Syndrome
18 year old woman developed early morning myoclonic jerks, well controlled with levetiracetam. Later developed progressive gait disturbances, visual disturbances, deafness and cognitive impairment. Muscle biopsy shows this.
Myoclonic epilepsy with ragged red fibers (MERRF)
What are these findings in the EEG?
Wicket spikes
16 year old presents with L sided weakness. Cerebral angiogram shows this.
MoyaMoya disease
A 44 year-old woman presented with the acute onset of confusion, ataxia, numbness and weakness in all four extremities.. MRI showed this.
ADEM
5 year old boy with regression of motor milestones, learning disabilities and visual disturbances. Also had fatigue, hypotension and skin hyperpigmentation. MRI showed this
Adrenoleukodystrophy
32 year old fireman presents with episodic paresthesia and weakness. Distribution as in the pic. NCS showing the following changes.
MADSAM
A 15-year-old girl with a history of frequent seizures and cognitive dysfunction. Her symptoms started at 13 years of age with occasional uncontrollable jerky movements of upper extremities followed later by generalized tonic-clonic seizures poorly controlled with multiple AEDs. Skin biopsy shows this.
Lafora body disease
38 year old gentleman with no significant vascular risk factors presents with recurrent subcortical strokes. On further questioning, he has severe burning paresthesia in feet and hands. His skin examination shows these.
Fabry's disease
50 year old gentleman with baseline mild memory issues, presented with acute onset stupor/ coma. MRI showed this.
Marchiafava- Bignami syndrome
7 day old girl, with no prenatal follow up, noted to have hypotonia, facial dysmorphism, corneal opacity and elevated CK in 2000s. (Photo insert)
Walker Warburg Syndrome (Congenital muscular dystrophy)
35 year old with progressive muscle stiffness and twitching (occurring even in sleep) for almost a year. (Video insert)