This phenomenon exacerbates MS symptoms by overheating.
What is Uhthoff's phenomenon?
100
Antibodies to aquaporin-4 is found in this disease.
What is Neuromyelitis optica (Devic's disease)?
100
This therapy does not affect long term outcome.
What is high dose corticosteroids?
100
63yr old with headache, anorexia, and ESR of 70 can have this disease, which is a neurologic emergency.
What is temporal arteritis?
100
You can never miss this!
34 yr old woman with a CN6 palsy on the left, disc edema bilaterally, and negative MRI brain.
What is Idiopathic Intracranial Hypertention (IIH)?
200
This study is abnormal in 90% of patient with a history of optic neuritis despite normal VA.
What is VEP?
200
This syndrome is associated with alcoholism, malnutrition, organ transplantation, and rapid correction of hyponatremia.
What is central pontine myelinolysis?
200
This interferon is given weekly.
What is Avonex?
200
A stroke caused by this kind of endocarditis in SLE.
What is Libman-Sacks endocarditis?
200
Beta amyloid is commonly seen in this type of dementia.
What is Alzheimer's Disease?
300
This percentage of RRMS develop SPMS by 25 years.
What is 75%?
300
This syndrome is characterized by a lot of diffusely enhancing lesions; often after a vaccination or a febrile illness in a 12 year old.
Bonus question: what is the more severe form of this syndrome, which is usually fatal?
What is ADEM?
Bonus: Hurst disease (Acute hemorrhagic leukoencephalitis)
300
This MS drug is well known for its cardiotoxic side effect.
What is Novantrone (mitoxantrone hydrochloride)?
300
A Turkish man with sinus thrombosis, retinitis, and oral and skins ulcers most likely has this disease.
What is Bechet's disease?
300
This neuromuscular disorder is seen in young male adults with unilateral arm weakness and atrophy without sensory involvement. He will most probably be Asian.
What is Hirayama's Disease (monomelic amyotrophy)?
400
This is a variant of MS, defined by confluent areas of enhancing hemispheric demyelination with mass effect and herniation.
What is Marburg?
400
Balo's concentric sclerosis characterizes this type of demyelination.
What is tumefactive MS?
400
This MS drug is a monoclonal antibody against alpha 4 integrin.
What is Tysabri (natalizumab)?
400
This is the most common connective tissue disorder with rare CNS involvement. However, the most common presentation is progressive compression neuropathy.
What is Rheumatoid arthritis?
400
This normal EEG variant is seen in awake patients in the central leads. It has a "combed" appearance.
What is mu rhythm?
500
This scale for defining disability in MS includes cognitive dysfunction.
What is the Multiple Sclerosis functional composite (MSFC)?
500
Focal demyelination of central area of corpus callosum in middle aged chronic alcoholics.
What is Machiafava-Bignami disease?
500
This drug is the first choice treatment in fatigue related to MS.
What is amantadine 100mg BID?
500
This syndrome can be associated with myasthenia gravis and polymyositis. These patients may present with trigeminal neuropathy.
What is Sjogren's Syndrome?
500
The circadian pacemaker is located here.
What is the suprachiasmatic nucleus of hypothalamus?