What are some Common MR pulse sequence used in Brain MRI?
T1WI (T1-Weighted Image)
T2WI (T2-Weighted Image)
FLAIR (Fluid Attenuation Inversion Recovery)
T2*WI (T2-star Weighted Image)
DWI (Diffusion Weighted Image)
What neurologic symptoms can be seen in spinal cord myelopathy?
loss of motor power and balance
loss of dexterity- objects slipping from hands
UMN deficit: rigidity, hyperreflexia, positive babinski
slow progressive step wise deterioration
What are some of the arteries in with large arterial infarction occur in?
Middle cerebral artery (MCA); most common
Anterior cerebral artery (ACA)
Posterior cerebral artery (PCA)
Vertebral artery (VA)
What are the features of T1WI?What shows bright on T1WI?What shows dark on T1WI?
Short TR and TE time
Fat- appears bright
fluid appears dark
part 2
fat
Subacute and chronic hemorrhage
melanin
protein-rich-fluid
slowly flowing blood
paramagnetic substances:gadolinium,manganese,copper
calcification(rarely)
part 3
Increased water,asinedema,tumor,infarction,inflammation, infection, hemorrhage (hyperacute or chronic)
low proton density,calcification
flow void
What are some disorders of the spine?
degenerative spine disease
Spinal cord or root entrapment ( herniated lumbar disc)
Spinal deformity
Osteoporotic vertebral fracture
Destructive (infectious and tumor related)
What are common sites of cerebral aneurysms?
Anterior communicating artery (A-com) 30~35%
Posterior communicating artery (P-com) 30~35%
Middle cerebral artery (MCA) 20%
Posterior circulation About 15%
What are some normal structures seen with the Intravenous contrast enhancement by Gadolinium? What are some pathological conditions seen with Intravenous contrast enhancement by Gadolinium
Arteries
Veins
Cerebral sinuses
Non brain structures
Tentorium
Falx
Choroid plexus
Nasal and paranasal sinus mucosa
Normal brain tissues is not enhanced due to BBB
Part 2
Tumors
Vascular diseases (aneurysm, AVM)
Capsule of brain abscess, empyema
Chronic subdural hematoma
Margin of recent infarction
Margin of radiation necrosis
What do degenerative changes that occur in C3-C7 presents as?
axial pain
myelopathy
radiculopathy
stiffness (lost of ROM)
weakness
loss of sensation
hyperreflexia, hypertonia
Spurlings sign
What are some types of vascular malformation?
Arteriovenous Malformation
Cavernous Malformations
Mixed Malformations
Telangiectasis
Vein of Galen Malformation
Venous Malformations
What are the features of T2WI?What shows bright on T2WI?What shows dark on T2WI?
part 1
TR: long
TE: long
fat: intermediate-bright
fluid: bright
part 2
increased water, as in edema, tumor, infarction, inflammation, infection, subdural collection
methemoglobin (extracellular) in subacute hemorrhage
Part 3
low proton density, calcification, fibrous tissue
paramagnetic substances: deoxyhemoglobin, methemoglobin (intracellular), iron, ferritin, hemosiderin, melanin
protein-rich fluid
flow void
What are the conservative treatments for disc herniation?
period of rest
NSAID
Physiotherapy
epidural corticosterioid injection
What are some common complications of aneurysm?
Vasospasm within 14 days of rupture Secondaryinfarction
Hydrocephalus
Seizure
Match the images to what they are showing
Image 6- T1WI hemorrhagic mass with perifocal edema
Image 7 T2WI edema and chronic hematoma
Image 8 Small lesions distributed in subcortical, external capsuled, deep white matter with few periventricle lesions
Image 9 -Normal brain MRS vs MRs of malignant glioma
What are the surgical indication for disc herniation and what is the surgical procedure?What are the surgical indications for spinal stenosis and what is the name of the procedure?
part 1
cauda equina syndrome
motor deficit
failure of 2 months of conservative treatment
Discectomy (only the herniated part)
Part 2
acute motor weakness
failure of 6 months of conservative treatment
spinal decompression: laminectomy
What are common diagnostic tools used to evaluation of vascular diseases?
carotid duplex (ultrasound)
Computed tomography (CT)
Magnetic Resonance Imaging (MRI)
Magnetic Resonance Angiogram (MRA)
Cerebral angiograph
Doppler ultrasound
Functional • Electroencephalogram (EEG)
Biochemistry • Lumbar puncture (spinal tap)