Psychopharm
Neuroanatomy
OTC
Neuroscience
Addiction
100

A 9-year-old child with ADHD does not respond to methylphenidate.  This medication should be tried next.

Amphetamine/ Dextroamphetamine

100

Dopaminergic neurons in the mesocorticolimbic system originate from this structure.

Substantia nigra 

100

This OTC supplement is used to target symptoms of trichotillomania.  

  N-acetylcysteine (NAC)

100

This neurotransmitter has a major role in the acute reinforcing effects of drugs of abuse.

Dopamine

100

This monthly long-acting medication can be used in the treatment of alcohol use disorder

Vivitrol (naltrexone ER)

200

Memantine exerts its cognitive preservation effects through this mechanism.  

NMDA receptor antagonism

200

This label indicates the insula in the coronal section of the cortex.

Answer: B

200

Taken prior to conception, this OTC may reduce the risk of major congenital malformations in women taking anti epileptic medications.

Folic Acid 

200

This neurotransmitter system most directly regulates impulsive or affective aggression. 

Serotonergic 

200

This substance is associated with the highest rate of conversion to schizophrenia or bipolar disorder.

Cannabis

300

This antipsychotic carries the lowest risk of QT prolongation.

Aripiprazole

300

This area of the brain is implicated in maintaining wakefulness. 

(Ascending) Reticular Activating System 

300

Co-prescription of this class of analgesics is likely to cause a clinically significant rise in lithium levels.

NSAIDs

300

This neurotransmitter is contained in sleep-promoting neurons of the ventrolateral preoptic nucleus.

GABA

300

Cigarette smoking induces the metabolism of this atypical antipsychotic.

Clozapine (or Olanzapine)

400

This is the mechanism of action of valbenazine, a medication used to treat tardive dyskinesia.

Vesicular Monoamine Transporter 2 (VMAT-2) inhibition

400

Histaminergic neurons that regulate sleep originate from this brain nucleus.

Tuboromammillary Nucleus (TMN)

400

A patient with a history of alcohol use disorder presenting with ataxia, nystagmus, and confusion is likely deficient in this vitamin.

Thiamine (B1)

400

This cell type is implicated in both neural circuit formation in the developing brain and scavenging for damaged neurons, plaques, and infectious agents.

Microglia

400

Most substances of abuse activate this dopaminergic pathway, leading to addictive behavior.

Mesolimbic 

500

In the CATIE study, this antipsychotic was considered most effective due to its low rate of discontinuation and high reduction in psychopathology.

Olanzapine

500

This label indicates the putamen.

A

500

A 72-year-old patient's examination is remarkable for profound sensory ataxia with loss of vibratory sensation and cognitive issues described as irritability, fluctuating with somnolence. This is the most likely nutritional deficiency associated with these findings.

Cobalamin (B12)

500

Developmental delay, cardiac abnormalities, palate defects, immune deficiency, and an increased risk of schizophrenia characterize this genetic syndrome.

DiGeorge Syndrome

500

Activation of this receptor is thought to be responsible for the anti-anxiety and sedative hypnotic effects of alcohol.

GABA-A