MOA
This catecholamine is the first-line vasopressor in septic shock due to its strong alpha-1 effects and minimal impact on heart rate compared to epinephrine.
What is norepinephrine?
This serious complication can occur when vasopressors like norepinephrine extravasate into surrounding tissue.
What is tissue necrosis?
This receptor is primarily responsible for norepinephrine's ability to increase systemic vascular resistance
What is alpha-1 receptor
What is = or >65
This medication stimulates alpha and beta receptors and is commonly used in cardiac arrest and as a continuous infusion in anaphylactic shock.
What is epinephrine?
Careful titration of epinephrine is important to prevent tachycardia due to stimulation of this receptor
What is beta-1 receptors
This airway intervention may be preferred over repeated racemic epinephrine treatments if a patient's airway continues to deteriorate
What is endotracheal intubation?
Instead of escalating epinephrine infusion in refractory anaphylaxis, this adjunct medication may be used to counteract vasodilation in patients with beta-blockers
What is glucagon?
In patients with severe asthma, this intervention may be used instead of racemic epinephrine when lower airway bronchospasm is the primary issue.
What are beta-agonist nebulizers (eg albuterol)
Compared to dopamine, this vasopressor is preferred in septic shock due to fewer arrhythmias and better outcomes.
What is norepinephrine?
In septic shock, this intervention is recommended before starting norepinephrine to optimize preload.
What is fluid resuscitation (IV or crystalloids)
For anaphylaxis, this route of epinephrine administration is preferred over a continuous IV drip in the prehospital setting.
What is intramuscular injection?
Due to its effect on β2-adrenergic receptors, which causes tocolysis, epinephrine opposes this hormones' actions on the uterus and may delay labor.
What is oxytocin?
This drug class can block the effects of adrenaline, paradoxically causing extreme high blood pressure and a slow heart rate (bradycardia)
Beta blockers
According to the Lancet, in this year English physician Henry Salter reported that “asthma is immediately cured in situations of either sudden alarm or violent fleeting excitements”.
What is 1859
A slang name for 1 mg of code-cart epinephrine (1:10,000 or 1:1,000) added to a 1L Saline bag for treating profound bradycardia or hypotension when a pharmacy-mixed drip is unavailable.
What is a dirty epi drip?