SABRIL
ONFI
LUNDBECK
XENAZINE
EPILEPSY
100
16%- 20% average reduction of this drug was reported when used with Sabril
What is Phenytion?
100
This is the number of patients randomized in the CONTAIN trial
What is 238?
100
Paramus, NJ
Where is Lundbeck's US Research located?
100
While taking Xenazine, call your doctor immediately if you have any symptoms of this syndrome which includes high fever, stiff muscles, problems thinking, uneven heartbeat or sweating.
What is NEUROLEPTIC MALIGNANT SYDROME OR NMS?
100
20-60% of these patients have a history of infantile spasms
What is LGS?
200
44% of patients on 3grams/day experienced this side effect while taking Sabril, according to the PI
What is headache
200
12 patients in the CONTAIN trial achieve this outcome?
What is seizure freedom?
200
This is the percentage of Lundbeck that is owned by the Lundbeck Foundation?
What is 70%?
200
About 7% of placebo patients had a 6 point or greater improvement of their Chorea scores. Xenazine patients had this percentage of improvement.
What is 50%?
200
This type of seizure generally lasts for 1-2 minutes, may have aura, automatisms, confusion and sleepy after.
What is CPS?
300
the time to maximum concentration (tmax) of Sabril
What is 1 hour?
300
Their starting dose should be 5mg/day for these patients, Patients should then be titrated up slowly according to weight, but to half the recommended dose.
What is the Elderly or Geriatric propulation?
300
This man founded Lundbeck in 1915 as a trading company
Who is Hans Lundbeck?
300
This drug class should be discontinued at minimum of 14 days before starting Xenazine and should never be prescribed together with Xenazine.
What are MAOi's?
300
This term refers to seizures that involve the whole brain at once
What are Generalized seizures?
400
In the Dean trial, 43 patients were randomized to this treatment group?
What is 3 grams?
400
Onfi tablets are white, round and debossed with a 5, 10 or 20 on one side of the tablet. These 2 letters are on the other side of the tablet.
What is LU?
400
Ulf's last name
What is Wiinberg
400
The recommended maximum daily dose for patients who are identified as CYP2D6 poor metabolizers
What is 50mg?
400
The Ketogenic diet is recommended for children from this age to age 12.
What is 2 years old?
500
What does GABA stand for?
What is gamma-aminobutyric acid?
500
This is the minimum weight criteria for the CONTAIN trial
What is 12.5kg?
500
This is the tag line that often appears next to the company logo on branded items
What is "Your Partner in Epilepsy"?
500
the elimination half life of tbz in patients with hepatic impairment
What is 17.5 hours?
500
This drug will be available in the US first quarter of 2013 for the adjunctive treatment of partial seizures in patients age 6-17
What is Oxcellar XR (oxcarbazepine)