Disease
It is the most common cause of dementia in the elderly, currently affecting 50 million people worldwide.
Alzheimer's disease
It is a component of both brain development and disease.
Neural degeneration
It's discovery stimulated major new treatment approaches that aim to treat CNS damage in human patients.
Neuroplasticity
This treatment promotes recovery from CNS damage through rehabilitative treatment.
Rehabilitative Training
It is the offending agent in synthetic heroin that was identified as the cause for developing severe parkinsonism in its users.
MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridin)
It is a factor in mammalian PNS that contributes to neural regeneration.
Schwann cells
This cell is a lasting source for transplantation because of its innate property to divide indefinitely and is pluripotent.
Stem Cells
In this condition, amputees continue to experience the limbs that have been amputated.
Phantom Limb
The progressive development and intensification of convulsions elicited by a series of periodic brain stimulations.
Kindling phenomenon
This is when axon branches grow out from adjacent healthy axons and synapse at the sites vacated by the degenerating axon.
Collateral sprouting
Transplanting appropriate fetal tissue into this part of the brain showed positive results in MPTP monkey model of Parkinson's disease.
Substantia Nigra
This is roughly equivalent to education and intelligence and is thought to play a role in the improvements observed after brain damage that do not result from true recovery of brain function.
Cognitive reserve
This proposes that many common neurodegenerative diseases result from the presence of misfolded proteins that initiate a chain reaction causing other proteins to misfold.
Pathogenic spread hypothesis
This is when degeneration spreads from damaged neurons to neurons that are linked to them by synapses.
Transneuronal degeneration
This is transplanting a patient’s own adrenal medulla cells into their striatum, usually for the treatment of Parkinson’s disease.
Adrenal Medulla Autotransplantation
This is where animals are exposed to group housing, toys, activity wheels, and changing stimulation to assess neurological benefits of cognitive and physical activity.
Enriched Environments