PHARMACOKINETICS
As we age, we have decreased perfusion, decreased functioning nephrons and GFR. These aspects effect what part of the pharmacokinetics category
What is excretion
If medications move thru this body system to rapidly, absorption may not occur
What is the small intestine
While taking Phenytoin, health teaching should include this regarding urine
May turn urine pinkish-red or reddish-brown
These types of dietary meals may increase the effects of Levodopa-Carbidopa
What are high protein meals
This medication takes 5 - 7 days to reach steady serum levels
What is Diazepam
At age 60 liver decreases in size, hepatic circulation decreases and hepatic liver enzymes are decreased. These factors effect which part of pharmacokinetics category
What is metabolism
Due to decreased absorption, this route is less than 100% bioavailable
What is the oral route
This herbal medication decreases the effect of Gabapentin
What is Ginko Biloba
Shuffling gait, stooped posture and mask-like facial expression are clinical manifestations of this disorder
What is Parkinson's disease
When a client experiences unexpected or opposite response to a medical drug treatment it is known as
Paradoxical effects
This is the "process occurring from time medication enters body to time entering bloodstream and circulation"
What is absorption
This route of administration is virtually 100% bioavailable
What is intravenous route
This medication prevents excitability which is caused by excessive stimulation
What is Phenytoin
This medication combination is a metabolic precursor of dopamine
What is Levodopa-Carbidopa
This beverage should not be taken with Imipramine
What is grapefruit juice
Decreased cardiac output, increased body fat, decreased body mass and serum albumin belong to which pharmacokinetics category
What is distribution
Muscle tissue has this component which makes IM injections absorbed rapidly
What is abundant blood supply
With Phenytoin, a decrease in these two body systems can result in toxicity and displacement of the medication
What is abnormal kidney function and hepatic impairment
During the first few weeks of taking Levodopa-Carbidopa, clients may experience this adverse effect
What is orthostatic hypotension
This adverse effect is caused by foods that include tyramine
What is hypertensive crisis
This laboratory value is the most reliable measure for evaluation of kidney function
What is GFR
Most medications applied by this route are prescribed for "local effects"
What is skin
To prevent gum disease and overgrowth of gum tissue (gingival hyperplasia), health teaching should include this
What is a "soft-tissue" toothbrush
Levodopa-Carbidopa is contraindicated in clients with this ocular (eye) disorder
What is narrow angle glaucoma
Aged cheeses, cured meats, pickled or dried foods all include this ingredient which should be avoided with Phenelzine
What is tyramine