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Coagulation Cascade
Labs
Drug Me
Vocab
Symptoms
100
This is also called "the Tissue Factor Pathway"
What is Extrinsic pathway
100
This lab test is used to monitor Heparin.
What is aPTT
100
I can be used to reverse Heparin and LMWH and I am made of fish sperm.
What is Protamine Sulfate
100
This is the term used to describe a round or macular lesion that can vary or change in color from black, yellow and green. Associated with bleeding.
What is Ecchymosis
100
This test can be used to diagnose PE- it allows comparison of ventilation and perfusion of the lung.
What is a V/Q scan
200
Which of the 5 stages of the Hemostasis process does fibrinogen convert to fibrin
What is Blood coagulation
200
These lab tests monitor Warfarin therapy.
What is pt/inr
200
I am an oral anticoagulant and should not be used in pregnancy. I am category X.
What is Warfarin
200
This term means low platelet level and can be an adverse effect of Heparin and LMWH.
What is Thrombocytopenia
200
Symptoms of this includes: unilateral edema, warmth and pain... Homans' sign is not always conclusive.
What is DVT
300
The intrinsic and extrinsic pathways lead to the activation of this factor.
What is Factor X
300
This is the recommended INR value for someone with a prosthetic heart valve.
What is 3-4.5
300
I have been recently put out on the market in the US as an oral anticoagulant and work by directly binding with factor Xa- inhibiting the production of thrombin.
What is Rivaroxaban (Xarelto)
300
This term is described as a round and purple macule from 1-2mm. Also a sign of bleeding.
What is Petechia
300
Symptoms of this includes chest pain, dyspnea, orthopnea, and tachypnea.
What is a PE
400
These 4 factors require vitamin K for synthesis.
What is Factors II, VII, IX, X
400
This lab test is recommended to monitor newer anticoagulants.
What is serum anti-Xa
400
I am a newer oral anticoagulation drug that is a direct thrombin inhibitor.
What is Dabigatran extexilate (Pradaxa)
400
Commonly called a nose bleed, I can be a sign of excessive bleeding.
What is epistaxis
400
A client with atrial fibrillation is receiving a continous heparin infustion. The nurse would determine the client is receiving the therapeutic level based on which of the following labs. a. Prothrombin time of 12.5 sec b. Activated partial thromboplastin time of 60 sec c. Activated partial thromboplastin time of 28 sec d. Activated partial thromboplastin time longer than 120 sec
What is b. Activated partial thromboplastin time of 60 seconds.
500
This enzyme degrades the fibrin meshwork of a clot.
What is Plasmin
500
This lab test is an effective screening test for DVT. It measures the amount of fibrin degradation in the plasma.
What is D-dimer
500
The only FXa inhibitor available for subcutaneous injection has a long half-live and lacks a specific reversal agent.
What is Fondaparinux
500
Commonly called right sided heart failure. This commonly occurs with patients concurrently with pulmonary embolism.
What is Cor Pulmonale
500
A client is admitted with pulmonary embolism and is treated with streptokinase. A nurse would report which of the following assessments to the physician before initiating this therapy. a. Adventitious breath sounds b. Temperature of 99.4 F orally c. Blood pressure of 198/110 mm Hg d. Respiratory rate of 28 breaths/min
What is c Blood pressure of 198/110 mm Hg. Thrombolytic therapy is contraindicated in severe hypertension due to risk of cerebral hemorrhage.