Cardiovascular
To prevent a patient developing tolerance to their nitroglycerin patch, the RN advised the pt to do this.
What is remove the patch at bedtime for at least 8 drug-free hours?
The division of the autonomic nervous system that is associated with the "rest/digest" response.
What is parasympathetic?
Muscarinic agonists activate muscarinic receptors that are associated with this division of the autonomic nervous system.
What is the parasympathetic nervous system?
Name 1 side effect of neuromuscular blockers.
What is paralysis?
The suffix used for alpha1 blocking drugs.
What is -osin?
This is the MOA of nitro.
What is venous dilation to reduce preload/cardiac oxygen demand?
The desirable quality of a drug that allows it to alter a specific disease process while leaving other physiologic processes largely unaffected.
What is selectivity?
This muscarinic agonist is the most effective medication for the treatment/prevention of motion sickness.
What is scopolamine?
This class of medication is the mainstay treatment of myasthenia gravis.
What are cholinesterase inhibitors?
Be prepared to administer this medication if a pt develops an anaphylactic reaction to an antibiotic.
What is epinephrine?
Risk of digoxin toxicity is increased in this disrupted electrolyte state.
What is hypokalemia?
This division of the autonomic nervous system is associated with the "fight or flight" response.
What is the sympathetic nervous system?
Muscarinic agonist used to treat urinary retention and is contraindicated for individuals with gastric ulcers, hypotension, asthma, hyperthyroidism, and/or urinary/bowel obstruction.
What is bethanechol [Urecholine]?
This class of medications works by preventing acetylcholine from activating nicotinic M receptors on the skeletal muscles and are used to facilitate surgery, intubation, and mechanical ventilation.
What are neuromuscular blocking agents?
Contraindications and cautions to use of this specific adrenergic antagonist class include sinus bradycardia, AV heart block, and asthma.
What are non-selective beta-blockers?
The RN should withhold digoxin if their cardiac assessment identifies this?
What is HR <60bpm or new irregular rhythm?
"Can't see, can't pee, can't spit, can't s**t" helps you remember this grouping of adverse effects.
What are anticholinergic side effects?
Urge incontinence associated with overactive bladder can be treated with this muscarinic antagonist.
What is oxybutynin [Ditropan]?
Name 2 side effects of cholinesterase inhibitors.
What is increased skeletal muscle contraction, bradycardia, bronchial constriction, urinary urgency, increased glandular secretions, increased tone/motility of GI tract, miosis?
This catecholamine is indicated for management of shock because it increases cardiac output to increase BP.
What is dopamine?
This is the definition of positive inotropic effect
What is increases force of contraction?
The division of the peripheral nervous system that is responsible for the voluntary movement of skeletal muscles.
What is the somatic nervous system?
Name 2 side effects of a cholinergic agonist
What are bradycardia, increased gland secretion (sweating, salivation, bronchial secretions), smooth muscle contraction (GI/lungs)?
Vecuronium must also be combined with these two medication classes.
What are anesthetics and analgesics?
When this event occurs with dopamine and epinephrine, severe tissue necrosis can occur and is treated with phentolamine, an alpha-adrenergic antagonist.
What is extravasation?
Class of medication that is contraindicated with nitroglycerin administration because it can cause profound hypotension.
What is phosphodiesterase-5 inhibitor?
The vascular system and prostate are primary controlled by which receptor subtype?
What are alpha-1 receptors?
Signs and symptoms associated with muscarinic poisoning/toxicity (must name at least 3).
What are bronchospasm, increased bronchial secretions, bradycardia, hypotension, profuse salivation, diarrhea, bowel/bladder incontinence, diaphoresis, tearing (lacrimation), and miosis?
Both malignant hyperthermia treatment and neuroleptic malignant syndrome are treated with this medication.
What is dantrolene?
Orthostatic hypotension, reflex tachycardia, and increased nasal congestion in a pt with BPH is likely caused by their medication from this class.
What is an alpha-1 blocker?
Foods to be avoided w/ digoxin.
What are high-fiber foods, like bran?
These are the three primary neurotransmitters of the peripheral nervous system.
What are acetylcholine, epinephrine, and norepinephrine?
The volume of atropine to be administered
Order: atropine (Atreza) 0.3 mg IM stat
Available: atropine (Atreza) 0.4 mg per mL
What is 0.75 mL?
Enzyme found in blood plasma that is responsible for breaking down succinylcholine and contributes to the drug's very short half-life.
What is pseudocholinesterase?
The major adverse effect of methyldopa
What is hepatotoxicity?