Immunity & Inflammation
RA
SLE
JIA
HIV/AIDS
100

Immune system cells have proteins on their surface that allows the body to identify the difference between its own healthy cells and non-self protein antigens.

What is self-tolerance?
100

RA primarily affects this part of the body.

What are synovial joints?

100

SLE primarily affects the cells that make up this type of tissue.

What is connective tissue?

100

True or False: Children with JIA have a negative rheumatoid factor 90% of the time.

What is true?

100

These are the different stages of HIV.

What is 

⚫Stage 1- Acute (Short)

⚫Stage 2- Chronic (Years to decades)

⚫Stage 3- AIDS (Significantly decreased CD4 count parameters and presence of an opportunistic infection)

200

This is a process where an inappropriate immunity develops to an adults own tissues.

What is autoimmunity or an autoimmune disorder?

200

These are late symptoms of RA.

What is increased inflammation and pain, morning stiffness, joint deformity, and skin lesions/nodules?

200

This is a type of lupus that is not systemic and only affects the skin.

What is discoid lupus? 

(Chronic cutaneous lupus erythematosus (CCLE) which is often characterized by a discoid (disk shaped) rash)

200

JIA is characterized by these symptoms.

What is joint pain, tenderness, and edema which can cause limping? Some systemic sx include fever, rashes, and delayed growth.

200

This lab finding is significant in the diagnosis of AIDS.

What is a CD4 count less than 200 cells/mm3?

300

Infections that occur more frequently or are more severe in individuals with weakened immune systems.

What is an opportunistic infection?

300

This is a life threatening complication of RA.

What is cervical subluxation?
300

These are a group of autoantigens that can be found in the nucleus of cells. Testing of these is important in the diagnosis and management of various autoimmune diseases such as SLE.

What are extractable nuclear antigens (ENAs)?

⚪anti–SS-a (Ro)

⚪anti–SS-b (La)

⚪anti-Smith (anti-Sm)

⚪anti-dsDNA

300

These are complications of JIA.

What is uveitis/blindness, Growth Retardation, Joint deformity, & Functional disability?

300

These are ways HIV can be transmitted.

What is sexually, parenterally, and perinatally? 

400

A significant decrease in these lymphocytes can indicate immunosuppression and increased susceptibility to infections.

What are CD4 cells?

400

This is a very specific and sensitive test to detect RA in the early stages, but it is also a marker for aggressive and erosive late-stage disease depending on the level.

What is anti-cyclic citrullinated peptide (anti-CCP)?

400

This medication used to treat SLE reduces B lymphocytes ability to produce autoantibodies.

What is Belimumab (Benlysta) monoclonal antibody therapy?

400

These are nursing considerations to manage symptoms of JIA.

What is manage fatigue, pain control, stress management, and mobility aids?

400

This class of medications works by altering the DNA and RNA of cells to prevent viral replication at different stages in the HIV life cycle; this can help to slow disease progression and improve life span.

What is combination antiretroviral therapy (cART)?

500

This is a non-specific and protective syndrome of normal tissue responses to cellular injury, allergy, or invasion of pathogens. It is an important part of general immunity.

What is inflammation?

500

This intervention completely removes the inflamed lining of an RA affected joint.

What is a synovectomy?

500

This is the leading cause of death in patients with SLE.

What is kidney damage (lupus nephritis & CKD)?

500

This is an important assessment to identify a life altering diagnosis in patients with JIA. 

What are regular vision screenings?

500

These are nursing considerations that are important to educate patients with HIV/AIDS about.

What is strict medication adherence, pain management, prevent infections, prevent the spread of disease, nutrition, and psychosocial preparations.