Dont be CRABI
Malignant plasma cells secrete this immunoglobulin, often used in the diagnosis and staging of multiple myeloma
What is m-protein or m-spike protein?
First in it's class and approved in 2014, this BiTE targets CD19 on ALL cells.
What is blinatumomab (Blincyto)?
Data ranked in a specific order where zero is an arbitrary value
The owner of Goldman's Pharmacy, where one might see a prescription being filled for Peter, Lois, Cleveland or Quagmire.
Who is Mort? (Family Guy)
A recent SBAR addressed the HIPEC with cisplatin Order Panel, which is being updated to 100 mg/m2 per NCCN and should be dispensed in this specific type of sterile container.
What is (multiple) syringes?
Once weekly dosing and the SQ route is preferred with this proteasome inhibitor as it reduces risk of neurotoxicity
What is bortezomib (Velcade)?
All BiTE agents bind to this protein on the surface of T-cells
What is CD3?
This type of error describes one in which the null hypothesis is true but was rejected anyway
What is a type 1 error?
Fired by the king, this miracle man's wisdom and knowledge embody that of Pharmacist, even covering his miracle pills in chocolate to help them go down.
Who is Miracle Max? (The Princess Bride)
The length of the observation time which is unnecessary after two doses of a SQ anti-CD38 agent have been well tolerated.
What is 30 minutes?
These medications may cause a false-positive indirect antiglobulin test, which is why a type-and-screen is recommended prior to initiation of therapy
What are daratumumab (Darzalex) and isatuximab (Sarclisa)?
BiTE therapies all contain this same black box warning, which is why they are usually dosed in a step-up regimen.
What is cytokine release syndrome?
A study with 80% power has this much risk for a type 2 error
What is 20%?
In fair Verona where we lay our scene, this famous apothecary once said:
"Within the infant rind of this weak flower
Poison hath residence and medicine power"
Who is Friar Lawrence? (Romeo and Juliet)
This was the guidance to providers on using Therapy Plans with the following in the title: “CC ALLGY”, "CC NE RHEUMATOLOGY", “CC RHEUMATOLOGY ASSOCIATES”, "CTGI", “GAFC”, "HHCMG”, "PACT", or "STARLING"
What is DO NOT USE?
Some BiTE therapies used for relapsed/refractory multiple myeloma target this antigen on the cancer cell, which normally helps to regulate the growth and survival of B cells.
What is BCMA (b cell maturation antigen)?
BiTE therapies used for relapsed/refractory multiple myeloma target this antigen on cancer cells, which normally helps to regulate the growth and survival of B cells
What is BCMA (B-cell maturation antigen) or GPRC5D?
This risk calculation indicates how much the risk is reduced in the treatment group compared to the control group. For example, a value of 0.43 indicates that the treatment group is 43% less likely to experience the event
What is relative risk reduction?
(1 - RR)
This small-time druggist employs George at his soda fountain. After he receives a telegram informing him of his son’s death and spends the day in a drunken stupor, he incorrectly fills a prescription for an ill child.
Who is Mr Gower? (from It's A Wonderful Life)
The names of two biosimilar TNF-alpha blockers that may be given over 1 hr as a "rapid" infusion if at least 4 previous doses well tolerated.
What is Renflexis and Inflectra? (will also accept Avsola)
Due to renal insufficiency, this three drug combo regimen would be a safer alternative to VRd.
What is CyBorD? (cycylophpsphamide, bortezomib, dex)
A BiTE approved for use in relapsed/refractory follicular lymphoma.
What is mosunetuzumab (Lunsumio) or epcoritamab (Epkinly)?
A study with two independent samples and continuous normally distributed data should use this type of statistical test
"It is odorless, tasteless, dissolves instantly in liquid, and is among the more deadly poisons known to man."
What is iocane powder? (from The Princess Bride)
Added to EPIC's Packaging and Compounding in 2024, this oral suspension for inpatient use can be ordered for patients with translocation 15:17 who have difficulty swallowing or a feeding tube.
What is tretinoin (oral suspension)?