ChemoMan &
Compounding
Adjunctive Treatment/ Complications
Infectious Diseases
Non-pharmacological Interventions
DDIs and Counseling Points
100

This drug class (or drug) does NOT cause myelosuppression.

What is bleomycin, 

100

This drug blocks the conversion of purines into uric acid and may be used for this complication.

Bonus:

Hyperkalemia, hypocalcemia, and hyperphosphatemia can present in the blood work. 

the complications that can occur with leukemia and non-Hodgkins lymphoma.

What is allopurinol?

What are the electrolyte deficiencies associated with tumor lysis syndrome? 

100

This drug has a contraindication with or within 2 weeks of MAO inhibitor use, such as amitripyline (Elavil (R)) .

What is linezolid or Zyvox? 

100

Seek shade, wear tightly woven fabrics and apply sunscreen are all advisories for protection against this type of cancer.

What is skin cancer? 

100

This folic acid pathway inhibitor  should be avoided in pregnancy and should be taken with a full glass of water. 

What is sulfamethoxazole/trimethoprim or Bactrim? 

200

These drugs can contribute to neurotoxicity and is available as a wafer. 

What are nitrosureas, and Carmustine? 

200

Initiate erythropoetin stimulating agents when ____ is above this level.

Hemoglobin (Hgb) <10g/dL 

200
A life-threatening organ dysfunction caused by a  dysregulated host response to infection. 


Bonus: 

Characterized by this scale. 

What is sepsis?


Bonus: What is SOFA score > or equal to 2?(acceptable alternates; qSOFA) 

200

Avoiding cold temperatures/cold beverages should be encouraged while currently on this regimen/drug class as part of one's chemotherapy cycle. 

What is oxaliplatin?

200

Use of alcohol should be avoided with this drug with anaerobic drug coverage and at least 3 days afterwards to combat this reaction. 

What is metronidazole or Flagyl, and a disulfuram-like response/reaction? 

300

This chemotherapy drug class can contribute to peripheral neuropathy.

What are taxanes?

300

Vistoguard can be used within 96 hours for overdose of to treat life-threatening toxicity from this agent.

What is fluorouracil?

300

Daily double: 

This antibiotic has no activity against these 3 species that start with the same letter. (two answers)  

What is tigecycline and Pseudomonas, Proteus, and Providencia species. 


300
Avoiding prolonged exposure to hot water, dishwashing gloves, jogging, chopping , gardening or yard work will help manage this syndrome. 

Capecitabine, 5-FU, cytarabine, TKIs, and liposomal doxorubicin can contribute to this. 

What is hand-foot syndrome management?

300

This drug can cause biliary sludging and kernicterus  in neonates. 

What is ceftriaxone? 

400

Protect from light for this chemotherapy drug can turn pink when decomposed. 

What is dacarbazine? 

400

True or False:

Atropine is used to prevent acute onset of diarrhea from this agent,

TRUE. 

What is irinotecan. 

400

If underweight, use this type of body weight for dosing. (applies to aminoglycosides) 

What is total or actual body weight dosing? 
400

Acupuncture or medical cannabis is commonly used as this type of therapy.

What is complementary ? 

400

This alkylating agent is a vesicant and the antidote for extravasation is  DMSO (dimethyl sulfoxide) and cool compresses. 

What is mitomycin? 

500

A glovebox for compounding hazardous drugs is referred to as this. 

What is compounding aseptic containment isolator?

500

Correcting anemia will only be adequately managed if these labs are also corrected. (3 labs) 

What are folate, iron, and B12? 

500
Frequent rinsing of the mouth, using a soft toothbrush and performing daily oral hygeine prevents this type of complication. 

BONUS: 

Treatment with these two agents may help lessen pain and make it possible to perform activities of daily living. 

What is the risk of oral Candida infection? 

What are nystatin oral suspension and clotrimazole troches?

500

Weight loss, physical activity, increased nutrition and absence of tobacco use are called this?

What are modifiable risk factors? 

500

Monitoring for this before and after treatment to reduce cardiotoxicity. 

What is LVEF using echogram or MUGA scan?