State of adaptation in which exposure to a drug causes changes in drug receptors that result in reduced drug effects over time.
What is opioid tolerance?
Cause of death with overdose of opioids.
What is respiratory depression?
The maximum daily dose of acetaminophen in healthy adults.
What is 4,000 mg/day?
Pain that occurs between doses of medication.
What is breakthrough pain?
Common side effects of opioids.
What are nausea, vomiting, constipation, itching?
Antidote for acetaminophen
What is acetylcysteine?
Contraindications to opioid use.
What are respiratory insufficiency, elevated intracranial pressure, morbid obesity/sleep apnea, paralytic ileus, pregnancy?
Opioid antagonist
What is naloxone?
Binds to an opioid pain receptor in the brain and causes the reduction of pain sensation.
What is an agonist?
Client education for opioid analgesics.
What are do not take the medication with alcohol or other CNS depressants, no driving or operating heavy machinery, increase fluids and add fiber/stool softeners to increase bowel movements, and activity as tolerated?
-zepam & zolam
What are suffixes for benzodiazepines?
Adverse effect associated with chronic use of acetaminophen
What are bleeding (with warfarin) and hepatotoxicity?
Opioid commonly used as an antitussive?
What is codeine?
Black Box Warning of opioids
Do not give opioids and benzodiazepines together
Nonopioid analgesic that is stronger than acetaminophen
What is tramadol?