War on Drugs
What was the main focus of the “War on Drugs”?
What is punished low-level users/distributors instead of focusing on treatment.
What must be present for opioid intoxication?
What is recent use + behavioral change (euphoria/dysphoria, impaired judgment)
Which drug relieves autonomic withdrawal symptoms?
What is Clonidine (Catapres®)
Which full μ-agonist is only available through certified clinics?
What is Methadone (Dolophine®, Methadose®)
Which is a full agonist vs partial agonist?
What is Methadone = full; Buprenorphine = partial (ceiling effect)
What disparity did the War on Drugs worsen?
What are the racial disparities in incarceration?
What eye finding is most common in intoxication?
What is miosis (pinpoint pupils)
Which OTC drug treats diarrhea in withdrawal?
What is Loperamide (Imodium®)
Which SL film/tablet combines buprenorphine and naloxone?
What is Suboxone® (2/0.5 mg, 8/2 mg)
Which drug is safer in overdose?
What is Buprenorphine (ceiling effect on respiratory depression)
Why did incarceration fail as a solution?
What is it did not equal rehabilitation or recovery.
How many symptoms are required for opioid withdrawal?
What is at least 3 (e.g., dysphoria, N/V, muscle aches, lacrimation, diarrhea, yawning, insomnia, fever)
Which drug is used for nausea/vomiting in withdrawal?
What is Ondansetron (Zofran®) .
Which buprenorphine product is a monthly SC injection?
What is Sublocade®
Which requires accredited clinics, and which can be prescribed outpatient?
What is Methadone = clinics only; Buprenorphine = office-based (± naloxone)
What effect did the War on Drugs have on treatment access?
What is it reduced access to addiction treatment programs.
Duration required for OUD DSM-5 diagnosis?
What is problematic pattern within 12 months
Which drug is used for anxiety in withdrawal?
What is Hydroxyzine (Vistaril®, Atarax®)
Which IM injection requires patients to be fully opioid-free before use?
What is Naltrexone (Vivitrol®)
When can buprenorphine be initiated?
What is only after mild withdrawal symptoms begin.
Name two long-term impacts of the War on Drugs.
What is increased incarceration rates, racial disparities, reduced rehabilitation, stigma against users
Name 3 DSM-5 OUD criteria.
What is using larger amounts, unsuccessful cut-down, craving, tolerance/withdrawal, continued use despite harm, role failures.
Which drug is often used for insomnia in withdrawal?
What is Trazodone (Desyrel®)
Which OUD maintenance drug has a half-life of 24–36 hours and must be tapered carefully?
What is Methadone (Dolophine®, Methadose®)
Which drug has more pregnancy safety data?
What is Methadone (Category C, historically more studied)