Oral Antihyperglycaemics

Management of T2DM

100

A 58 y/o man with severe CKD is recently diagnosed with T2DM. What is the first-line treatment?

Sulfonylurea (Glipizide, Gliclazide, Glibenclamide) + either:

- SGLT2i OR

- GLP1 RA

200

A 30 y/o woman has T2DM with elevated HbA1c levels, mild non-proliferative diabetic retinopathy. What is the target HbA1c range?

6.0-6.5%

Metformin

100

Name 1 medical condition that is contraindicated with Metformin

- severe CKD

- severe HF

- liver dysfunction

200

Name 2 symptoms of lactic acidosis

any 2 of the 4:

- fast, shallow breathing

- decreased appetite

- persistent vomiting & abdominal pain

- feel cold

Hypoglycaemia

100

What is the range for hypoglycaemia?

≤ 4.0 mmol/L

200

Explain what is the 15-15 rule.

15g of fasting-acting sugars, followed by 15 min wait before checking blood glucose again