Terms
Risk Factors
Pathophysiology
Clinical Manifestaitons
Exam Questions
100

Joint that is freely movable.

What is Diarthrodial Joints or Synovial Joints?

100

This condition increases mechanical stress on joints and is a major factor that leads to osteoarthritis.

What is obesity?

100

Small bone fragments or cartilage breaking off into the joint space.

What is "joint mice"?

100

Stiffness, swelling, and pain at the joint.

What is early symptoms?

100

A nurse is educating a group of older adults about osteoarthritis. Which statement by a participant indicates a correct understanding of the disease process?

  • A) “Osteoarthritis is an autoimmune disease that attacks my joints.”
  • B) “This condition leads to cartilage breakdown and joint space narrowing.”
  • C) “Osteoarthritis primarily affects non-weight-bearing joints.”
  • D) “Osteoarthritis is always caused by previous joint injuries.”

What is ‘This condition leads to cartilage breakdown and joint space narrowing’ (B)?

200

Bony projection or growth that can occur from osteoarthritis (Bone Spurs). 

What is Osteophytes?

200

This protein is damaged by osteoarthritis , leading to thinning cartilage. 

What is collagen?

200

The enzyme that breaks down proteoglycans, reducing cartilage hardness.

What are proteases?

200

Feeling like a joint isn't as strong or as stable as it usually is/ a joint looking noticeably different than it used to be.

What is gradual onset?

200

A patient with osteoarthritis reports increased pain in the knees. The nurse expects which clinical findings? (Select all that apply.)

  • A) Joint stiffness that improves with movement
  • B) Symmetric joint involvement
  • C) Crepitus with joint movement
  • D) Heberden’s and Bouchard’s nodes
  • E) Pain relieved with activity

What are ‘Joint stiffness that improves with movement, crepitus, and Heberden’s/Bouchard’s nodes’ (A, C, and D)?

300

Large molecules that improved elasticity and stiffness and provide resistance to compression in articular cartilage.

What is Proteoglycans?

300

This gender is most likely to develop osteoarthritis. 

What is female?

300

Hypertrophy of bone and narrowing of joint spaces occur from subchondral bone exposure. 

What is loss of articular cartilage?


300

Percentage of people over the age of 55 affected by osteoarthritis. 

What is 80%?

300

A 65-year-old obese patient with a history of knee osteoarthritis asks the nurse how to slow disease progression. Which recommendation is most appropriate?

  • A) Increase high-impact exercises like running
  • B) Avoid all weight-bearing exercises
  • C) Consider weight loss and low-impact exercises
  • D) Increase daily intake of calcium supplements

What is ‘Consider weight loss and low-impact exercises’ (C)?

400

Cells responsible for reabsorption of bone matrix and release of calcium/phosphate from bone. 

What is Osteoclasts?

400

Overuse of this drug, inhibits chondrocyte growth, can lead to osteoarthritis. 

What is steroids? 

400

This can be used or early detection of osteoarthritis.

What is MRI?

400

Osteoarthritis in multiple joints often occurs due to this process, where the body shifts movement patterns to reduce stress on the affected area.

What is joint compensation?

400

Which diagnostic finding is most characteristic of osteoarthritis?

  • A) Joint space narrowing and osteophyte formation on X-ray
  • B) Elevated rheumatoid factor (RF)
  • C) Positive anti-nuclear antibody (ANA) test
  • D) Increased erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP)

What is ‘Joint space narrowing and osteophyte formation on X-ray’ (A)?

500

Cells responsible for producing collagen/proteoglycans. Their death is associated with the progression of Osteoarthritis.

What is Chondrocytes?

500

Low impact exercise, wearing protective gear, and regular check ups.

What is preventative measures?

500

The enzyme that breaks down proteoglycans, reducing cartilage hardness.

What is proteases?

500

This manifestation worsens with activity and disease progression and most often presents as this.

What is unilateral pain?

500

A 32 year old female ultra marathon runner comes into the clinic complaining of hip pain and is diagnosed with osteoarthritis. Which factor is most likely to be the cause of osteoarthritis in this case?

  • A) Trauma/Injury
  • B) Mechanical
  • C) Steroid use
  • D) Age/Gender

What is 'Mechanical' (B)?