Basics of OI
What body material is defective in Osteogenesis Imperfecta?
Collagen
Which type is the mildest?
Type I
Which test confirms the genetic mutation causing OI?
DNA analysis
What should a nurse avoid when lifting a child with OI?
Lifting under the armpits
Name the most common medication for OI.
Bisphosphonates
What is the most common visible sign of OI?
Blue sclera
Which type is the most severe and often fatal in infancy?
Type II
Which imaging test shows fractures and deformities?
X-ray
What technique is safest for repositioning?
Lift using open palms to support the whole body
What is one side effect of bisphosphonates?
Hypocalcemia
Is OI inherited or random?
Usually inherited but can be a spontaneous mutation
Which type is severe but survivable and causes progressive deformities?
Type III
What protein is reduced or defective in OI?
Type I collagen
What should parents avoid in the home to prevent fractures?
Clutter or tripping hazards
What therapy helps improve mobility and reduce fractures?
Physical therapy
What is the medical term for ‘brittle bones
Osteogenesis Imperfecta
Which type involves hyperplastic callus formation?
Type V
What type of OI has normal collagen quantity but poor collagen quality?
Type II
What is the biggest danger during routine handling?
Twisting movements
Surgery in OI often involves placing what device in bones?
Intramedullary rods
Which bones are at highest risk for fractures in OI?
Long bones (arms & legs)
Which type is linked to CRTAP gene defects?
Type VII
What organ system is MOST at risk besides bones
Respiratory system
Which emergency symptom must be reported immediately
Sudden chest pain and difficulty breathing
What nutrition is crucial for bone health in OI?
Calcium and Vitamin D