Show:
Pharmacodynamics 1
Pharmacodynamics 2
CNS Part 1
CNS Part 2
Cardiac Part 1
100
The amount of drug needed to elicit an effect is:
What is potency/efficacy
100
the most important property of a drug:
What is Effectiveness
100
For which drug does the FDA recommend genetic testing for patients of Asian Descent: Selegeline, Donepezil, Phenelzineu, Carbamazepine.
What is Carbamazepine.
100
Which drug for the treatment of Alzheimer's Disease is recommended for moderate to severe AD?
What is Memantine (Namenda)
100
JNC 8 states that the following antihypertensive is one of the first line treatments for hypertension:
What is a Ca channel blocker
200
When a disease process triggers increased metabolism of a drug, the disease has altered the drug's:
What is Pharmacokinetics
200
Information available for a medication a nurse is preparing to administer states that the drug is "highly lipid soluble". What would be the nurse's expectation regarding how easily this drug would pass through a cell membrane?
What is the drug would pass through easily.
200
What is true about the neurotransmitters: Too much dopamine is associated with psychosis, Too much serotonin is associated with depression, Too little dopamine is associated with alzheimer's disease, too much acetylcholine is associated with alzheimer's disease.
What is Too much dopamine is associated with psychosis.
200
Which drug facilitates the availability of levodopa in the central nervous system?
What is Carbidopa
200
Mr. Evans, a 57 year old patient with T1DM, has proteinuria. Which anti-hypertensive medication would be the first choice?
What is ACE Inhibitors
300
When compared with a drug having a therapeutic index of 20, a drug with a therapeutic index of 2 would be considered which of the following with regard to the margin of safety?
What is less safe.
300
A patient has been taking a drug with a narrow therapeutic index for one week. What is the most significant implication for the nurse who is caring for this patient: The drug will be ineffective, because it will have difficulty reaching the minimum effective concentration, The patient's body will maintain therapeutic levels easily, The patient's kidney function may be compromised, The patient should be monitored carefully for toxicity.
What is The patient should be monitored carefully for toxicity.
300
Which is correct about the pharmacologic treatment for parkinsonism: Benztropin (Cogent) enhances the anti-cholinergic effects of L-dopa, Vitamin B-6 increases the effectiveness of levodopa, Administration of dopamine is an effective treatment for parkinsonism, Levodopa/Carbidopa (Sinemet) can be associated with dysrhythmias.
What is Levodopa/carbidopa (Sinemet) can be associated with dysrhythmias.
300
Patients starting cholinesterase inhibitors for Alzheimer's Disease should be instructed that they may experience which side effects?
What is Nausea, vomiting and diarrhea.
300
The advantage of the new direct renin inhibitor, aliskirin, over an ACE inhibitor.
What is less problems with cough and angioedema
400
Which characteristic inhibits the crossing of the drugs through the cell membrane?
What is ionization
400
On monday a patient begins taking a daily dose of a drug with a half-life of 1 day. If the patient takes the same dose every day, on what day will the plasma drug levels reach a plateau?
What is Friday.
400
A 26 year old patient has been taking an anti-epileptic medication for 8 years since a head injury and has been seizure free for the past 7 years/ Recent EEG was WNL. He wants to discontinue the seizure medication. What is the best response from the health care provider: Stop the medication. Keep an accurate seizure chart to see if the medication needs to be restarted, wait ten years after last seizure and then it is safe to stop the medication, Anti-epileptic medications are needed for life, the dose must be gradually reduced so as not to precipitate seizures.
What is the dose must be gradually reduced so as not to precipitate seizures.
400
An 82-year-old man with Alzheimer's Disease has a cold and c/o stuffiness and a runny nose. If the pt takes a cholinesterase inhibitor, the nurse should remember to avoid using which type of drugs to relieve the cold symptoms?
What is Diphenhydramine (Benadryl)
400
Which is true about diuretics: Hypokalemia can be avoided by combining a thiazide diuretic with spironolactone, potassium sparing diuretics produce significant diuresis, the principle adverse effect of spironolactone is hypokalemia, thiazide diuretics produce the greatest amount of diuresis.
What is hypokalemia can be avoided by combining a thiazide diuretic with spironolactone.
500
The prescriber has just ordered a new medication for a patient and has ordered a larger dose than is normally indicated. The patient questions the nurse and asks why the dose is so large. The nurse would be correct to explain that:
What is the initial dose is sometimes higher to reach a therapeutic level more quickly.
500
A drug that produces its effect by preventing the activation of a receptor by endogenous molecules and drugs would be classified as:
What is an antagonist
500
What is the goal of pharmacologic therapy in treating Parkinson's Disease?
What is Balance cholinergic and dopaminergic activity in the brain.
500
The generic name for the drug Marcaine is:
What is Bupivicaine
500
This calcium channel blocker is considered most cardiac specific
What is Verapamil