Are you smarter than a P1?
What is the weight of 0.72 L of polyethylene glycol 400 (SG = 1.13)? Round your answer to the nearest tenth.
813.6 g
Calculate the milliequivalents of a standard ammonium chloride (MW = 53.5 g/mol) 54 mg/mL sterile solution in a 350 mL container. Round to the nearest tenth.
353.3 mEq
A patient received 2 mg of IV morphine. What is an equivalent dose of oral hydromorphone? (10 mg of IV morphine is equivalent to 7.5 mg of oral hydromorphone) Round to the nearest tenth.
1.5
A patient is taking clozapine and is at the clinic for a routine visit. Today’s labs include WBC 2617 cells/mm3 with 32% segs and 7% bands. Calculate the patient’s ANC. Round to the nearest whole number.
1021
Which of the following medications warrants monitoring for pulmonary fibrosis?
A. Amiodarone
B. Hydralazine
C. Nabumetone
D. Imodium
Amiodarone
A cough syrup contains 3.2 grams of brompheniramine maleate per liter. How many milligrams are contained in one teaspoonful of the elixir? Round to the nearest whole number.
16 mg
How many millimoles of calcium chloride (MW = 147 g/mol) are represented in 132 mL of a 7.5% (w/v) calcium chloride solution? Round to the nearest hundredth.
67.35 mmols
A patient is to receive acyclovir 7.5 mg/kg every 12 hours for an acute outbreak of herpes zoster. What daily dose, in milligrams, should a 197-pound female receive? Round to the nearest whole number.
1343 mg
HW is a 52-year-old female (height 5’3”, weight 132 pounds) with MSSA endocarditis. Her labs include SCr 0.8 mg/dL. The physician wants to pick an antibiotic based upon her renal function and calls you, as the pharmacist, for a recommendation. What is creatinine clearance of HW? Round to the nearest whole number.
68 mL/min
Which of the following statins is least likely to be involved in a drug interaction?
A. Atorvastatin
B. Simvastatin
C. Pravastatin
D. Rosuvastatin
Pravastatin
What is the pH of a solution containing 0.32 mole of a weakly basic drug and 0.08 mole of its salt per liter of solution (pKa of the drug = 8.62)? Round to the nearest hundredth.
9.22
WR is a 25-year-old male that will be receiving Clinimix (Amino acids 4.25%/Dextrose 10%) daily at a rate of 75 mL/hr. How many calories will WR receive each day? Round to the nearest whole number.
918
If phenobarbital elixir contains 16.8 mg of phenobarbital per 8 mL, how many grams of phenobarbital would be used in preparing a pint of the elixir? Round to the nearest hundredth.
0.99 g
How many milliosmoles of CaCl2 (MW = 111 g/mol) are represented in 185 mL of a 15% (w/v) calcium chloride solution? Round to the nearest whole number.
750 mOsm
A 78-year-old white male with a history of atrial fibrillation, hypertension, GERD, and CHF is currently receiving metoprolol tartrate 25 mg twice daily, digoxin 0.25 mg daily, omeprazole 20 mg daily, Pepcid 40 mg at bedtime, and aspirin 81 mg daily. Recent labs reveal an elevation in creatinine of 1.8 mg/dL. 6 months ago, creatinine was 1.1 mg/dL. Other information: height = 6 feet 2 inches, weight 178 lbs., blood pressure = 128/78 mmHg, Pulse = 62 bpm, Respiration rate = 21 breaths per minute.
Which medication is this change in creatinine most likely to require dose adjustments?
A. Metoprolol tartrate
B. Pepcid
C. Omeprazole
D. Aspirin
E. Digoxin
Pepcid
What is the ratio strength (w/v) of 85 mL containing a 1:25 (w/v) ammonia solution diluted to 1 liter? Round to the nearest whole number.
1:294
A 46-year-old female with radiation enteritis is receiving 1650 kcal from her parenteral nutrition. The solution contains amino acids, dextrose, and electrolytes. There are 72.5 grams of protein in the PN and it is running at 110 mL/hour over 24 hours. What is the final concentration of dextrose in the PN solution? Express the answer as a percentage. Round to the nearest whole number.
15%
GS is a 62-year-old female hospitalized with decompensated heart failure and fever. Cultures are positive for aspergillosis. GS weighs 98 kg and will receive 0.25 mg/kg/day of amphotericin B (reconstituted and diluted to 0.1 mg/mL) by IV infusion. How many milliliters of amphotericin solution are required to deliver the daily dose? Round to the whole number.
245
An intravenous infusion contains 3 mL of a 1:800 (w/v) solution of epinephrine and 500 mL of D5W. At what flow rate (mL/min) should the infusion be administered to provide 0.5 mcg/kg/min of epinephrine to a 65 kg patient? Round to the nearest whole number.
4 mL/min
Which of the following is a common complication with the use of paclitaxel?
A. Retinopathy
B. Neuropathy
C. Rash
D. Cystitis
Neuropathy
A patient will be started on daily oral digoxin for management of atrial fibrillation. The following pharmacokinetic parameters for oral digoxin are known: F=0.6, Vd=500 L/day, and Cl=120 L/day. When would steady state be reached? Round to the nearest day.
14 days
A patient is to receive a potassium acetate infusion prepared by adding 12 mL of a 39.2% potassium acetate (KC2H3O2) to 0.45% NS to make 1 liter. The patient is to receive the potassium acetate at 7 mEq/hr. What rate (mL/hr) will provide this dose? Round to the nearest whole number. (MW of K = 30, MW of C2H3O2 = 59)
146
ML is a 189-pound male receiving a premixed dopamine drip (650 mg/250 mL) in the ICU. The order states that the drip can be titrated to a maximum dose of 15 mcg/kg/min. What is the maximum rate (mL/hr) at which the drip can be run? Round to the nearest whole number.
30
A hospice pharmacist receives a prescription for a 1% morphine sulfate oral solution. She has a 150 mL bottle of morphine sulfate labeled 15 mg/5 mL and a 260 mL bottle of morphine sulfate labeled 95 mg/5 mL. How much of the 95 mg/5 mL product must be mixed with the contents of the 15 mg/5 mL morphine sulfate bottle to prepare the desired percentage strength for the patient?
192.9 mL
A 67-year-old African American male has a history of hypertension and bipolar disorder. He is currently taking hydralazine, hydrochlorothiazide, loratadine and lithium. He has been feeling a little off lately. Labs/vitals reveal: Creatinine = 1.1 mg/dL, potassium = 4.0 mEq/L, sodium = 142 mEq/L, TSH = 17.4 mIU/mL, lithium 0.9 mEq/L, BP = 156/78 mmHg
Of his other medications, which medication would be most likely to cause lithium levels to rise?
A. Hydralazine
B. Loratadine
C. Hydrochlorothiazide
D. None of the above would interact
HCTZ