Non-opioids
These two medication classes are first-line for most cases of mild-to-moderate acute pain.
What are acetaminophen and NSAIDs?
Opioid receptor responsible for analgesia and respiratory depression.
What is the mu receptor?
The max daily dose of Tylenol for an adult is this
What is 4,000 mg/day
This is the antidote used for opioid overdose.
What is naloxone?
A 24-year-old female presents with acute ankle sprain.
PMH: none
Meds: none
Pain score: 6/10
No allergies.
What is the best initial pharmacologic treatment?
What is Ibuprofen?
A patient with uncontrolled HTN should avoid this drug class
What is NSAIDs?
The first line treatment for opioid induced constipation (hint: 2 answers)
What are stimulant or osmotic laxatives?
Morphine 10 mg IV equals this oral mg dose of morphine.
What is 30 mg?
Antidote for acetaminophen toxicity.
What is N-acetylcysteine (NAC)?
A 72-year-old male presents with acute low back strain.
PMH: CKD stage 4, HTN
Meds: lisinopril, furosemide
What is the safest analgesic option?
What is Acetaminophen?
Maximum duration of ketorolac therapy due to GI/renal risk.
What is 5 days?
This drug has a boxed warning for life threatening QT-prolongation
What is methadone?
The oral dose of 7.5 mg of hydromorphone equal this IM dose in mg.
What is 1.5 mg?
This opioid should be avoided in breastfeeding due to ultra-rapid CYP2D6 metabolism risk.
What is codeine?
A 40-year-old male with acute dental pain.
PMH: Seizure disorder
Meds: levetiracetam
Which opioid should be avoided?
What is tramadol?
NSAIDs can increase the levels of this drug.
What is lithium?
Buprenorphine/naloxone is used to treat this
What is opioid use disorder (OUD)?
This is the dose range of Tylenol for a 28 kg child.
What is 280-420 mg every 4-6 hours?
(10-15 mg/kg Q4-6 hours)
A contraindication of this drug is a sulfonamide allergy
What is celecoxib (Celebrex)
A 65-year-old male with acute shoulder pain.
PMH: Peptic ulcer 1 year ago
Needs NSAID therapy.
What should be added?
What is a proton pump inhibitor?
IV indomethacin is used 14 days after birth for this reason
What is closing the patent ductus arteriosus (PDA)
Pharmacists should check this before dispensing a patient opioids
What is their states prescription drug monitoring program (PDMP) database?
This is the dose and days on morphine needed to convert to fentanyl patch
What is 60 mg/day for at least 7 days?
All opioids shoul be taken with food to decrease nausea except this drug.
What is oxymorphone?
A patient presents 6 hours after ingesting 10 grams acetaminophen.
What tool determines need for antidote?
What is Rumack-Matthew nomogram?