Clinical Manifestations
Pathophysiology/Effect on organ systems
Diagnosis
Treatment
Miscellaneous
100

Progressive loss of bone microarchitecture often silent until a vertebral body collapses.

What is Vertebral compression fracture?

100

Bone resorbing cells that break down bone tissue faster than it can be replaced

What is a overactive osteoclasts?

100

Low-impact fractures in older adults often reveal this underlying condition

What is a fragility fracture indicating underlying bone disease?

100

A bone medication that helps promote the formation of bones and increase bone density by stimulating osteoblast activity.

What is bone-building medication/anabolic agent?

100

A certain demographic of women who are screened for bone density loss when they reach this stage in life.

What is menopausal women?

200

Spinal pain with tenderness after some stress, often linked to collapse of a single vertebral body

What is Acute vertebral compression fracture?

200

Reduced thoracic cavity expansion due to spinal deformity

What is Restrictive lung effect?

200

Assessment of age, hormone levels, and medication history helps identify risk

What is risk factor–based screening?

200

These medications work by inhibiting osteoclast activity to reduce bone resorption

What are bisphosphonates?

200

A certain process that involves the repeated breakdown and rebuilding of bones.

What is bone remodeling?

300

Abnormal forward curvature of the upper spine

What is Kyphosis (dowager's hump)?

300

Immobility after hip fractures increase the risk of clot formation that can travel to the lungs

What is Pulmonary embolism or thrombosis?

300

This tool predicts the 10-year probability of fractures using clinical data

What is the FRAX assessment tool?

300

Adequate intake of these nutrients is essential to maintain bone strength and prevent worsening

What are calcium and vitamin D?

300

A specialized cell that works towards building bone in your body.

What is osteoblast

400

Gradual reduction in standing height due to repeated collapse of spinal vertebrae

What is Loss of height?

400

Limited mobility leading to loss of muscle mass and strength over time

What is Muscle atrophy?

400

This measurement compares a patient’s bone density to that of a young adult

What is a T-score?

400

The use of testosterone or estrogen to help maintain bone density within older males or postmenopausal women.

What is hormone therapy?

400

A specialized cell that works toward breaking down bone in your body.

What is osteoclast?
500

Bones become fragile and break easily

What is a Fragility fractures?

500

Bones become fragile due to the loss of calcium

what is decreased bone density (or bone demineralization)?

500

This scan is used to confirm decreased bone density and diagnose the condition

What is a DEXA scan?

500

Lifestyle interventions focusing on mechanical stress can help slow progression of this condition

What is weight-bearing exercise?

500

Milk, yogurt, or cheese are foods recommended to individuals who face bone density loss because they are full of this nutrient that helps builds bone.

What is calcium?