SITAGLIPTIN
SITAGLIPTIN + METFORMIN HYDROCHLORIDE
DAPAGLIFLOZIN
ENDOCRINE SYSTEM
DIABETES
100

Which of the following is a primary benefit of sitagliptin for Type 2 diabetes patients?

Reduces postprandial blood glucose levels

100

Which hormone's activity is prolonged by sitagliptin's inhibition of DPP-4?

GLP-1 (Glucagon-like peptide-1)

100

What is a common side effect of dapagliflozin related to fluid balance?

Dehydration

100

What hormone does the pancreas produce to lower blood sugar levels?

 Insulin

100

What is the primary cause of high blood sugar in Type 2 diabetes?

Insulin resistance

100

Sitagliptin is typically taken in combination with which other type of diabetes medication?

Metformin

100

The combination of sitagliptin and metformin is typically not recommended for patients with:

 Moderate renal impairment

100

What condition is dapagliflozin used to treat in addition to Type 2 diabetes?

Heart failure

100

Which gland is responsible for regulating the body’s metabolism through the secretion of thyroxine?

Thyroid gland

100

What is the primary function of insulin in the body?

 To store glucose in the liver and muscles

300

What hormone is primarily affected by the action of sitagliptin to control blood glucose levels?

GLP-1 (Glucagon-like peptide-1)

300

Why is sitagliptin not associated with significant weight gain in Type 2 diabetes therapy?

 It does not significantly increase insulin secretion

300

What is the most common adverse effect related to the genitourinary system for patients on dapagliflozin?

Urinary tract infections

300

What is the primary function of the pancreas in the endocrine system?

Secretion of insulin and glucagon to regulate blood sugar levels

300

What is the main action of sulfonylureas in the treatment of Type 2 diabetes?

To increase insulin secretion

300

What is a key difference between sitagliptin and sulfonylureas?

Sitagliptin does not increase insulin secretion on its own

300

What is the most appropriate monitoring parameter for patients on metformin and sitagliptin combination therapy?

Blood glucose and renal function

300

What is the brand name of Health Prescription’s  Dapagliflozin product?

Glucusuria

300

Which hormone secreted by the thyroid gland helps regulate calcium levels in the blood?

Calcitonin

300

What is a common symptom of diabetic neuropathy?

 Numbness or tingling in the hands and feet

750

What is a contraindication for using sitagliptin in patients with Type 2 diabetes?

History of pancreatitis

750

What would require dose adjustments for the combination of metformin and sitagliptin?

Renal impairment

750

What is the role of dapagliflozin in patients with chronic kidney disease (CKD) and Type 2 diabetes?

 It decreases the progression of kidney damage and reduces albuminuria

750

What causes the overproduction of thyroid hormones in hyperthyroidism?

Autoimmune disorders, such as Graves' disease

750

What is a pathophysiological mechanism that primarily contributes to the hyperglycemia seen in Type 2 diabetes?

Overproduction of glucagon leading to increased hepatic glucose production