"It's not a tumor"
(or is it??)
(or is it??)
These two sites are "sanctuaries" for leukemia cells
What are the CNS and testes?
An otherwise healthy child with a platelet count of 10K, 1 week after a viral illness is likely to be treated with one of these agents
What are IVIG, and steroids?
Two common causative agents of hemorrhagic cystitis
What are ifosfamide and cyclophosphamide?
A patient on chronic antibiotic therapy may have an abnormal PT due to deficiency of this
What is Vitamin K?
Percentage of kids who survive standard risk ALL
What is 90%? (or even higher!)
The metabolic hallmarks of tumor lysis syndrome
What are hyperkalemia, hyperphosphatemia, hyperuricemia, and hypocalcemia?
A toddler who is profoundly neutropenic when well and has a normal ANC when ill is likely to have this form of chronic neutropenia
What is autoimmune neutropenia?
Cumulative exposure to this group of agents can lead to cardiomyopathy
What are anthracyclines?
A common reason for a prolonged PTT in a preop child
What is a lupus anticoagulant? (or what is a lab artifact/error?)
A new treatment for refractory ALL that shows great promise (and has recently helped one of our patients!)
What are CD19+ CARTs? (chimeric antigen receptor T-cells)
A patient with Beckwith-Wiedemann syndrome is most likely to have this type of tumor
What is Wilms tumor?
A child with abnormal thumbs, microcephaly, and pancytopenia may have this, which is a defect in DNA repair
What is Fanconi anemia?
A patient whose blood pressure drops during a chemotherapy infusion may have just received this agent
What is etoposide?
This intranasal agent may raise the level of an important clotting protein for some patients with this disorder
What is ddAVP? What is Type I von Willebrand's disease?
Two of the many organizations that help children with cancer
What are Make-a-Wish, St. Baldrick's, Friends of Karen, etc.?
The most likely site of metastatic disease for patients with bone and soft tissue sarcomas
What are the lungs?
A patient with red, irritated eyes may have just received this agent
What is cytarabine?
Hemarthrosis in a young boy is likely associated with a deficiency of one of these two factors
What are Factor VIII and IX?
Sometimes treating kids with cancer is sad, but discussions about end of life can be aided with this tool
What is MOLST?
MIBG scans are positive in patients with these tumors
What is neuroblastoma and pheochromocytoma?
The reason leucovorin doesn't rescue cancer cells from high dose methotrexate
What is leucovorin's ability to allow some nucleic acid synthesis despite dihydrofolate reductase inhibition?
A factor deficiency that is not diagnosed by an abnormal PT/PTT
What is Factor XIII deficiency?
The definition of palliative care
What is interdisciplinary care and symptom management in a situation where the focus is no longer on cure?