Clinical Patterns
Complications & Sequelae
Treatment Decisions
Lab Clues
Mimics
100

This JIA subtype presents with asymmetric arthritis in a toddler and primarily affects the knees 

Oligoarticular JIA 

100

This silent eye complication is most associated with ANA-positive JIA 

Chronic anterior uveitis 

100

First-line medication for oligoarticular JIA 

NSAIDS with or without IA steroids

100

This lab marker is used to primarily assess risk of uveitis 

ANA

100

This vasculitis presents with palpable purpura on the lower extremities with associated ankle and foot swelling 

Henoch-Schonlein Purpura 

200

This JIA subtype is associated with quotidian fevers and a salmon-colored rash 

Systemic JIA

200

This growth abnormality results in a longer limb due to increased blood flow from sustained inflammation 

Leg length discrepancy 

200

This is the first line DMARD for polyarticular JIA

Methotrexate 

200

In MAS, this inflammatory marker is paradoxically low or normal 

ESR 

200

This pediatric condition presents with fever greater than or equal to 5 days with associated mucocutaneous findings 

Kawasaki Disease 

300

This JIA subtype presents in an adolescent male with back pain, enthesitis, and HLA-B27 positivity 

Enthesitis related arthritis 

300

These jaw complications occur due to TMJ involvement in JIA 

Micrognathia/Retrognathia 

300

These biologics are first-line treatment for systemic JIA

IL-1 or IL-6 inhibitors 

300

This genetic marker is strongly associated with enthesitis-related arthritis 

HLA-B27 

300

This orthopedic condition occurs in overweight adolescents and causes hip pain 

Slipped Capital Femoral Epiphysis 

400

This JIA subtype resembles adult rheumatoid arthritis and has a more aggressive disease course 

RF positive polyarticular JIA 

400

This life-threatening complication of systemic JIA is marked by very high ferritin 

Macrophage Activation Syndrome (MAS) 

400

This medication is not effective for sacroiliitis in ERA 

Methotrexate 

400

This lab value is markedly elevated in MAS and helps distinguish it from a flare 

Ferritin 

400

This benign condition presents with nighttime leg pain without associated joint swelling 

Growing Pains 

500

This JIA subtype may be diagnosed without rash if there is nail pitting and a family history of psoriasis 

Psoriatic JIA 

500

This ocular finding involves calcium deposition in the cornea 

Band keratopathy 

500

These biologics are used when ERA does not respond to NSAIDs

TNF inhibitors 

500

This condition may mimic JIA but presents with cytopenias, elevated LDH, uric acid 

Acute lymphoblastic leukemia (ALL) 

500

This condition is associated with AVN of the femoral head in young male patients 

Legg-Calvé-Perthes Disease