Peever History: Past Theses
Techniques
Homeostatic Sleep, Circadian Rhythms, and Clock Genes--Oh My!
Neurodegenerat-ion
Miscellaneous
200

Patti Brooks found that these neurotransmitters are responsible for generating skeletal muscle atonia.

What are GABAA, GABAB, and glycine?

200

The most common technique used to assess attention in both rodents and humans.

What is the 5-choice serial reaction time test (5-CSRTT)?

200

This type of glial cell is thought to play an important role in sleep homeostasis.

What are astrocytes?

200

These are the two main pharmaceutical treatments for RBD.

What are melatonin and clonazepam?

200

Which primary author published a paper saying "we continuously increased the number of animals until statistical significance was reached to support our conclusions"?

Who is Yang Dan?

400

Sara Pintwala saw no behavioral changes after transplanting immortal orexin cells into this region, but did after transplanting into the dorsal raphe.

What is the lateral hypothalamus?

400
This technique is used to tag specific neurons and subsequently record their activity through electrophysiology.

What are optrode recordings?

400

This electrophysiological feature during sleep recovery is a sign of previous sleep deprivation.

What are increased slow oscillations during NREM sleep?

400

This membrane protein is a part of the glymphatic system and is responsible for fluid clearance.

What is AQP4 (aquaporin-4 water channel)?

400

The first track on the Peever Christmas album.

What is Baby It's Cold Outside?

800

After optogenetically inhibiting this type of cell in this region, Negar Golmohammadi saw no effects to REM sleep.

What are GABAergic neurons of the vlPAG?

800

This technique is used to profile gene expression at the level of a single-cell.

What is single-cell RNA sequencing (snRNA-seq)?

800

This german term describes any external stimuli that alter sleep drive.

What is a zeitgeber?

800

This class of neurons is most susceptible to dysfunction in all neurodegenerative diseases.

What are excitatory neurons?

800

In the wild, these three species of mammals only sleep for 2 hours each night.

What are horses, elephants, and giraffes?

1000

Christian Burgess discovered this after activating α1 receptors in orexin KO mice.

What is a reduction in cataplectic behaviors? 
1000

This technique uses immune cells to target and kill GFP-expressing cells.

What are JEDI T-cells?

1000

These two clock genes peak at the beginning of the night in diurnal animals. 

What are PER and CRY?

1000

The former name of multiple system atrophy.

What is Shy-Drager syndrome?

1000

The amount of spill kits the Peever lab owns. 

What are two?

2000

In 2003, Jimmy Fraigne determined that this respiratory condition causes sleep disruption at high altitudes in cats.

What is hypocapnia? 

2000

This tissue processing technique replaces opaque lipids with clear hydrogel, allowing researchers to take 3-dimensional images of the brain.

What is CLARITY?

2000

The SCN receives non-photic information from the pineal gland and this region, contributing to the circadian rhythm of our bodies. 

What are the serotonergic raphe nuclei (dorsal and median)?
2000

A rare, inherited disease that causes the progressive breakdown of neurons. 

What is Huntington's disease?

2000

What is the anterior-posterior distance between the red nucleus and the SLD?

What is 0.85-0.90 mm?